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Amino acids bind to phase-separating proteins and modulate biomolecular condensate stability and dynamics Nature

The RNA-binding E3 ligase MKRN2 selectively disrupts Il6 translation to restrain inflammation Nature

Steviol rebaudiosides bind to four different sites of the human sweet taste receptor (T1R2/T1R3) complex explaining confusing experiments Nature

The molecular dissection of TRIM25’s RNA-binding mechanism provides key insights into its antiviral activity Nature

Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains Nature

Structural mechanism for specific binding of chemical compounds to amyloid fibrils Nature

Translational T-box riboswitches bind tRNA by modulating conformational flexibility Nature

Accurate de novo design of high-affinity protein-binding macrocycles using deep learning Nature

Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus Nature

Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk Nature

Temperature dependent in vitro binding and release of target DNA by Cas9 enzyme Nature

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Nature

DynamicBind: predicting ligand-specific protein-ligand complex structure with a deep equivariant generative model Nature

Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly Nature

TREX reveals proteins that bind to specific RNA regions in living cells Nature

Geometric deep learning of protein–DNA binding specificity Nature

Bicarbonate-binding catalysis for the enantioselective desymmetrization of keto sulfonium salts Nature

Mechanisms of SARS-CoV-2 entry into cells Nature

Design, structure and plasma binding of ancestral β-CoV scaffold antigens Nature

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation Nature

Dual modality feature fused neural network integrating binding site information for drug target affinity prediction Nature

ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers Nature

Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase Nature

Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel Nature

Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding Nature

Measuring anion binding at biomembrane interfaces Nature

deoxyfluoro-analogues reveals differential recognition by glycan-binding partners Nature

SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks Nature

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation Nature

Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1 Nature

A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes Nature

Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins Nature

Programming inactive RNA-binding small molecules into bioactive degraders Nature

Molecular basis of CTCF binding polarity in genome folding Nature

Alternative splicing and related RNA binding proteins in human health and disease Nature

Canadian government moves to end Air Canada strike, seeks binding arbitration Reuters

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine | Cellular & Molecular Immunology Nature

A large-scale binding and functional map of human RNA-binding proteins Nature

Label-free, real-time monitoring of membrane binding events at zeptomolar concentrations using frequency-locked optical microresonators Nature

Limited conservation in cross-species comparison of GLK transcription factor binding suggested wide-spread cistrome divergence Nature

promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement Nature

Weak CO binding sites induced by Cu–Ag interfaces promote CO electroreduction to multi-carbon liquid products Nature

A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2 Nature

The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications Nature

Strategies for developing DNA-encoded libraries beyond binding assays Nature

Direct binding of TFEα opens DNA binding cleft of RNA polymerase Nature

Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19 Nature

Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography Nature

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Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding The Lancet

metabolite enables transcriptome-wide mapping of binding sites Nature

The Time Bind - Hochschild - 1997 - WorkingUSA Wiley Online Library

Receptor binding by a ferret-transmissible H5 avian influenza virus Nature

Jennifer Trouton. The ties that bind meer.com

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