BioLum Sciences

Leveraging biomarker analysis with an integrated approach, BioLum is transforming precision medicine and early disease detection. Our highly-sensitive, selective assays, diagnostics, and lab services provide insights for more efficient therapeutic R&D. With a focus on reactive oxygen, nitrogen, and sulfur species (RONSS), BioLum's assays outperform gold standards (including Griess & DAF). Our advanced chemiluminescence improves signal-to-noise by eliminating background autofluorescence, ensuring superior accuracy and precision with broad specimen compatibility. We work with pharmaceutical companies and researchers through preclinical discovery and development. To optimize treatment efficacy in complex diseases, it's critical to have a deep understanding of signaling pathways, mechanisms of action, and cellular interactions. Capabilities and services: -biomarker analysis -compound library screening -efficacy testing -rapid evaluation methods -custom assay synthesis -small molecule synthesis -drug repurposing -quantitative and qualitative insights -early target identification and validation -ADME -dose dependency testing -in vitro analysis -PK/PD -formula optimization -probe synthesis and development Our assays are designed for HTS with clinical translation and ease-of-use in mind. Reactive species are implicated in a range of diseases, including inflammation, cardiovascular (CAD, HF, PAH), respiratory (asthma, COPD), neurological, pain, tumor microenvironments, and immune-related.