B2B From breast to bone

To shed light on the bone metastatic process, B2B aims to develop a breakthrough technology that for the first time dissects the steps of spontaneous breast cancer metastasis to the bone and captures the 3D complexity of the process. The B2B device includes macro-size organoids from breast tumor and bone, assembled together with a macro-to-micro vascular network. This level of physiological complexity is required to capture the key elements of the metastatic process.