Clarity Bio Systems

Our team of experts can help you with all your metabolomics needs, including study design, LCMS data acquisition and analysis, and Metabolic modeling. Our software uses deep-learning tools to remove noise and degenerate features from the mass spectrometry data and presents high-quality results. Here are our services: (i) Consulting: A carefully designed protocol is a key for the success of metabolomics studies. Most metabolites are not only present in small quantities in biological fluids but are also fragile. A well-designed experimental pipeline can yield significantly better results and a wider metabolome coverage. We can help you with experiment planning and choosing between different sample preparation protocols, LC and MS methods, data acquisition modes and settings, and internal standards. (ii) LCMS data acquisition: We offer data acquisition services on a high-resolution AB Sciex Triple TOF 5600+ mass spectrometer coupled to Shimadzu UHPLC. We have extensive experience with reverse phase, HILIC, and reverse-phase ion-pairing chromatography. (iii) LCMS data analysis: Our proprietary software performs all steps of data analysis, including pre-processing, peak picking, noise removal, identification and removal of degenerate features such as in-source fragments, adducts and isotopes, data cleaning/filtering, quantification of peak area, metabolite identification, statistical analysis, and interactive plotting. Our AI-powered software incorporates the latest algorithms and statistical tools for biomarker discovery. We can save you months in data analysis time, resulting in faster publication or submission to regulatory agencies. Based on your needs, we can also offer our expertise for data anlysis with open source software. (iv) Metabolic modelling: Our pipeline can help you gain greater insights from the metabolomics or other omics data via interactive pathway mapping and visualization and with modelling tools such as flux balance analysis (FBA).