The fidelity of cellular processes that control and execute the biosynthesis of mRNA and proteins declines with age and when challenged by external stressors. This decline results in the production of physiologically unfavorable quantities (amounts) and poor quality (e.g. erroneous sequence, altered folding, or localization) of mRNA and proteins. We and others have shown that this fidelity decline contributes to disease mechanisms and to age-associated physiological changes. Whereas some of the processes involved in either mRNA or protein biosynthesis have been studied at great detail, an integrated, comprehensive view of the systemic consequences of fidelity decline is lacking. This Collaborative Research Centre (CRC) aims to address how fidelity changes in mRNA and protein biosynthesis collectively impact cellular and organismal functions.
Company Details
- Founded
- -
- Address
- Cologne, De
- Industry
- Research Services
- NAICS
-
Scientific Research and Development ServicesResearch and Development in the Physical, Engineering, and Life SciencesResearch and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Website
- https://crc1678.uni-koeln.de/
- HQ
- Cologne
- Competitors
- CECAD Cologne, Institute for Technology and Humanity, Cambridge Existential Risks Initiative, World Muscle Society, Cambridge Centre for Data-Driven Discovery, Stratocore, Nanovaccine Institute, imAGEin Erasmus Mundus Joint Master : International Master on the Biology of Ageing, Arise Innovations, Forethought.
Crc 1678 Questions
Crc 1678's website is https://crc1678.uni-koeln.de/
Crc 1678's LinkedIn profile is https://de.linkedin.com/company/crc1678
Crc 1678's industry is
Research Services
Crc 1678's top competitors are
Cecad Cologne,
Institute For Technology And Humanity,
Cambridge Existential Risks Initiative,
World Muscle Society,
Cambridge Centre For Data-Driven Discovery,
Stratocore,
Nanovaccine Institute,
Imagein Erasmus Mundus Joint Master : International Master On The Biology Of Ageing,
Arise Innovations,
Forethought.
Crc 1678's categories are Research Services
Crc 1678's founding year is 2024
