Cyclerion

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Our current portfolio includes novel clinical-stage assets, namely praliciguat and olinciguat, as well as multiple research stage molecules. Praliciguat is a systemic sGC stimulator that is exclusively licensed to Akebia and is being advanced in rare kidney disease. Olinciguat is a vascular sGC stimulator that Cyclerion intends to develop itself or out-license for cardiovascular diseases. Concurrently, we are also evaluating other activities aimed at enhancing shareholder value, which potentially include collaborations, licenses, mergers, acquisitions and/or other targeted investments. In addition, Cyclerion holds 10 percent equity ownership in Tisento Therapeutics as part of an asset purchase agreement in which Tisento acquired the brain-penetrant sGC stimulators zagociguat and CY3018.

Company Details

Employees
12
Founded
-
Address
Cambridge, Ma 02142, Us
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
Keywords
Manager jobs.
HQ
Cambridge, MA
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News

Cyclerion Announces Transformational Relaunch as a Neuropsychiatric Company - Yahoo Finance

Cyclerion Announces Transformational Relaunch as a Neuropsychiatric Company Yahoo Finance

Cyclerion cycles through latest pivot, reinventing itself as neuro biotech - Fierce Biotech

Cyclerion cycles through latest pivot, reinventing itself as neuro biotech Fierce Biotech

Cyclerion stock soars after MIT licensing deal to relaunch company - Investing.com

Cyclerion stock soars after MIT licensing deal to relaunch company Investing.com

Insiders Rewarded With US$55k Addition To Investment As Cyclerion Therapeutics Stock Hits US$7.6m - simplywall.st

Insiders Rewarded With US$55k Addition To Investment As Cyclerion Therapeutics Stock Hits US$7.6m simplywall.st

Cyclerion Therapeutics’ Licence Move: Boost or Bust? - StocksToTrade

Cyclerion Therapeutics’ Licence Move: Boost or Bust? StocksToTrade

Cyclerion Therapeutics Relaunches with Neuropsychiatric Focus - TipRanks

Cyclerion Therapeutics Relaunches with Neuropsychiatric Focus TipRanks

Cyclerion Therapeutics jumps on MIT deal to develop depression drug - TradingView

Cyclerion Therapeutics jumps on MIT deal to develop depression drug TradingView

Why Did Cyclerion Therapeutics Stock Surge Nearly 50% After-Hours Today? - Stocktwits

Why Did Cyclerion Therapeutics Stock Surge Nearly 50% After-Hours Today? Stocktwits

Cyclerion Therapeutics Inc (CYCN) Quarterly 10-Q Report - qz.com

Cyclerion Therapeutics Inc (CYCN) Quarterly 10-Q Report qz.com

How Cyclerion Therapeutics Inc. stock performs after earnings - July 2025 Short Interest & Safe Entry Point Alerts - Trung tâm Dự báo KTTV quốc gia

How Cyclerion Therapeutics Inc. stock performs after earnings - July 2025 Short Interest & Safe Entry Point Alerts Trung tâm Dự báo KTTV quốc gia

A struggling biotech wraps its main assets into a new drug company - BioPharma Dive

A struggling biotech wraps its main assets into a new drug company BioPharma Dive

Bio Startup Tisento Launches With $81M and a Brain-Penetrating Drug in the Clinic - MedCity News

Bio Startup Tisento Launches With $81M and a Brain-Penetrating Drug in the Clinic MedCity News

Cyclerion Therapeutics (CYCN) Secures MIT Licensing for Strategi - GuruFocus

Cyclerion Therapeutics (CYCN) Secures MIT Licensing for Strategi GuruFocus

The Rise and Fluctuation of Cyclerion Therapeutics Inc.: Key Insights into Its Recent Market Trends - timothysykes.com

The Rise and Fluctuation of Cyclerion Therapeutics Inc.: Key Insights into Its Recent Market Trends timothysykes.com

Cyclerion Announces Reverse Stock Split - Yahoo Finance

Cyclerion Announces Reverse Stock Split Yahoo Finance

Cyclerion signs MIT license for treatment-resistant depression program - Investing.com

Cyclerion signs MIT license for treatment-resistant depression program Investing.com

Tour de biotech: Cyclerion peddles through another disease area, laying off 45% amid heel turn toward mitochondria - Fierce Biotech

Tour de biotech: Cyclerion peddles through another disease area, laying off 45% amid heel turn toward mitochondria Fierce Biotech

Can Cyclerion Therapeutics Inc. stock beat analyst upgrades - Market Sentiment Review & Technical Buy Zone Confirmations - Trung tâm Dự báo KTTV quốc gia

Can Cyclerion Therapeutics Inc. stock beat analyst upgrades - Market Sentiment Review & Technical Buy Zone Confirmations Trung tâm Dự báo KTTV quốc gia

Cyclerion fails sickle cell test, prompting pivot to CNS disease - Fierce Biotech

Cyclerion fails sickle cell test, prompting pivot to CNS disease Fierce Biotech

Cyclerion Appoints Regina Graul, Ph.D., as President - citybiz

Cyclerion Appoints Regina Graul, Ph.D., as President citybiz

Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease - Frontiers

Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease Frontiers

Cyclerion Therapeutics Stock skyrockets by over 60%: Is the Surge Sustainable? - timothysykes.com

Cyclerion Therapeutics Stock skyrockets by over 60%: Is the Surge Sustainable? timothysykes.com

Will Cyclerion Therapeutics Inc. stock recover faster than peers - July 2025 Snapshot & Capital Efficiency Focused Ideas - Trung tâm Dự báo KTTV quốc gia

Will Cyclerion Therapeutics Inc. stock recover faster than peers - July 2025 Snapshot & Capital Efficiency Focused Ideas Trung tâm Dự báo KTTV quốc gia

Can Cyclerion Therapeutics Inc. stock deliver surprise earnings beat - Earnings Growth Summary & Free Weekly Watchlist of Top Performers - Trung tâm Dự báo KTTV quốc gia

Can Cyclerion Therapeutics Inc. stock deliver surprise earnings beat - Earnings Growth Summary & Free Weekly Watchlist of Top Performers Trung tâm Dự báo KTTV quốc gia

sGC stimulator praliciguat suppresses stellate cell fibrotic transformation and inhibits fibrosis and inflammation in models of NASH - PNAS

sGC stimulator praliciguat suppresses stellate cell fibrotic transformation and inhibits fibrosis and inflammation in models of NASH PNAS

Will Cyclerion Therapeutics Inc. stock recover faster than peers - July 2025 Summary & Growth Focused Entry Point Reports - Trung tâm Dự báo KTTV quốc gia

Will Cyclerion Therapeutics Inc. stock recover faster than peers - July 2025 Summary & Growth Focused Entry Point Reports Trung tâm Dự báo KTTV quốc gia

Member Spotlight: Q&A with Cyclerion Therapeutics - Massachusetts Biotechnology Council

Member Spotlight: Q&A with Cyclerion Therapeutics Massachusetts Biotechnology Council

Cyclerion reveals data for schizophrenia therapy - PharmaTimes

Cyclerion reveals data for schizophrenia therapy PharmaTimes

How Cyclerion Therapeutics Inc. stock reacts to inflationary pressures - July 2025 Spike Watch & High Accuracy Swing Entry Alerts - Fundação Cultural do Pará

How Cyclerion Therapeutics Inc. stock reacts to inflationary pressures - July 2025 Spike Watch & High Accuracy Swing Entry Alerts Fundação Cultural do Pará

Maturing Ironwood is spinning off Cyclerion, its edgy, risk-taking kid brother - statnews.com

Maturing Ironwood is spinning off Cyclerion, its edgy, risk-taking kid brother statnews.com

Ironwood Pharma Spins off Cyclerion Therapeutics With 5 Orphan Disease Compounds - BioSpace

Ironwood Pharma Spins off Cyclerion Therapeutics With 5 Orphan Disease Compounds BioSpace

Beneficial Metabolic Effects of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in a Mouse Diet-Induced Obesity Model - Frontiers

Beneficial Metabolic Effects of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in a Mouse Diet-Induced Obesity Model Frontiers

CYCN Stock Price and Chart — NASDAQ:CYCN - TradingView

CYCN Stock Price and Chart — NASDAQ:CYCN TradingView

BioMed Realty signs Cyclerion Therapeutics to 114,454 s/f lease at 301 Binney St. in East Cambridge, Mass. - NEREJ

BioMed Realty signs Cyclerion Therapeutics to 114,454 s/f lease at 301 Binney St. in East Cambridge, Mass. NEREJ

Why Did Cyclerion Therapeutics Stock Surge Nearly 50% After-Hours Today? - MSN

Why Did Cyclerion Therapeutics Stock Surge Nearly 50% After-Hours Today? MSN

Slate Path Owns 16.5% Cyclerion Stake, Lobbies For Changes - 24/7 Wall St.

Slate Path Owns 16.5% Cyclerion Stake, Lobbies For Changes 24/7 Wall St.

Cyclerion drug's 4-pronged cracking of neurodegenerative diseases passes early test - Fierce Biotech

Cyclerion drug's 4-pronged cracking of neurodegenerative diseases passes early test Fierce Biotech

Cyclerion Therapeutics (NASDAQ:CYCN) Trading 3% Higher – Here’s Why - Defense World

Cyclerion Therapeutics (NASDAQ:CYCN) Trading 3% Higher – Here’s Why Defense World

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