Emmace Consulting AB

Emmace offers excellence in advising and performance testing of pharmaceutical products on a CRO-basis and base the service on: -Traditional testing of inhalers (DPI, pMDI, and Nebulisers) using cascade impactors, laser diffraction and delivered dose uniformity characterisation according to US and EU Pharmacopeias. -Prediction of lung dose from inhalers by using a novel and validated in vivo realistic in vitro method including anatomically realistic mouth-throat models/inlets in combination with patient-like inhalation profiles. -experts in rAPSD planning and testing -Dissolution testing of Lung dose -Provides advising in CMC and clinical support as well as Lung dose modelling. -Offers Mimetikos Preludium, a lung deposition software. -Offers anatomical throats from the OPC consortium -Tests according to ISO 18562 under ISO 17025 accreditation Analytical instrumentation available at Emmace: -Impactors -Next generation impactor (NGI) -Andersen cascade impactor (ACI) -Multi stage liquid impinger (MSLI) -DUSA set ups -Mixing inlet -Breath Profile Generator F-SIG 6300 (Replay of inhalation profile) -Anatomical throat models for lung dose prediction -Mechanical hand for pMDI (Dose fire coordination with inhalation profile) -Spraytec Laser diffraction system equipped with inhalation cell -Spray Patter and Plume geometry (Envision system from Oxford lasers) -Aerodynamic particle sizer (APS) 3321 equipped with 3306 Impactor inlet -Faraday cages set up (electrostatic measurement) -UV-Vis Spectrometer