ExOcular Dx, Inc.

About Us ExOcular is revolutionizing the management of severe eye diseases. We're developing a portfolio of blood-based multiplex tests built on exosome-based, disease-specific biomarkers. These tests provide early, and actionable insights, paving the way for personalized and transformative patient care. We empower physicians with unparalleled insights to deliver earlier, more effective treatments. The Impact of Severe Eye Disease The incidence and prevalence of severe eye diseases increase as people age. Our initial focus is on patients with early- to intermediate-stage age-related macular degeneration (AMD) and diabetic retinopathy (DR)— the leading causes of blindness. Age-Related Macular Degeneration (AMD) The macula is crucial for central vision. AMD is a progressive retinal disease and a leading cause of irreversible blindness in people over 60. About 20M Americans have been diagnosed with AMD, 3x the number of patients with Alzheimer’s. Worldwide, 300M cases are projected by 2040. Diabetic Retinopathy (DR) BR is the most common complication of diabetes and the leading cause of blindness for Americans aged 25-74. About 9.6 million Americans, or 26% of patients with diabetes, are affected by DR. Our Solution Early Diagnosis Diagnostic testing is especially important for people over 50 and diabetics who are at higher risk for developing eye diseases. ExOcular results can help optimize referrals to ophthalmologists and drive intervention earlier. Progression Prognosis A test to risk-stratify patients could guide early intervention. Treatment Monitoring Serial testing can optimize dosing schedules and indicate if medications need to change. This strategy personalizes treatment, enhances health outcomes, and saves costs on ineffective specialty drugs.