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Resolution limit of the eye — how many pixels can we see? Nature

Maternal factor OTX2 regulates human embryonic genome activation and early development Nature

SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade Nature

Observation of constructive interference at the edge of quantum ergodicity Nature

Transients in the Palomar Observatory Sky Survey (POSS-I) may be associated with nuclear testing and reports of unidentified anomalous phenomena | Scientific Reports Nature

Volume 646 Issue 8086, 23 October 2025 Nature

Trump links autism and Tylenol: is there any truth to it? Nature

Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport Nature

Sperm sequencing reveals extensive positive selection in the male germline Nature

Learning the natural history of human disease with generative transformers Nature

Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity Nature

Horizontal and vertical exoplanet thermal structure from a JWST spectroscopic eclipse map Nature

T cell population expansion and effector differentiation in chronic infection and cancer Nature

Is it time for the Browns to trade Myles Garrett? Dawgs By Nature

The combined impact of fisheries and climate change on future carbon sequestration by oceanic macrofauna Nature

Western Indian subantarctic phytoplankton blooms fertilized by iron-enriched Agulhas water Nature

NFL trade rumor: Browns open to trading veteran defender Dawgs By Nature

Carbon footprint of the construction sector is projected to double by 2050 globally Nature

Sex differences in the association of wearable accelerometer-derived physical activity with coronary heart disease incidence and mortality Nature

Genome of an early Okhotsk individual reveals ancient admixture between Jomon and Kamchatka lineages Nature

The global biomass of mammals since 1850 Nature

Intrinsically accelerated cellular degradation is amplified by TDP-43 loss in ALS-vulnerable motor neurons in a zebrafish model Nature

Prediction of neural activity in connectome-constrained recurrent networks Nature

Sex differences in the association of physical activity with coronary heart disease incidence and mortality Nature

Habitual video gaming predicts multitasking performance while the role of cognitive capacity remains inconclusive Nature

Coral die-off marks Earth’s first climate ‘tipping point’, scientists say Nature

A long-necked early dinosaur from a newly discovered Upper Triassic basin in the Andes Nature

Aboveground biomass in Australian tropical forests now a net carbon source Nature

Addictive-like behavioural traits in pet dogs with extreme motivation for toy play | Scientific Reports Nature

Creative experiences and brain clocks Nature

Lithium deficiency and the onset of Alzheimer’s disease Nature

Ancient DNA connects large-scale migration with the spread of Slavs Nature

Redox-driven mineral and organic associations in Jezero Crater, Mars Nature

A prudent planetary limit for geologic carbon storage Nature

Induction of experimental cell division to generate cells with reduced chromosome ploidy Nature

Respiratory viral infections awaken metastatic breast cancer cells in lungs Nature

One mother for two species via obligate cross-species cloning in ants Nature

A brain-wide map of neural activity during complex behaviour Nature

Flourishing chemosynthetic life at the greatest depths of hadal trenches Nature

Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs Nature

Imidazole propionate is a driver and therapeutic target in atherosclerosis Nature

Association of SARS-CoV-2 vaccination status with risk of influenza-like illness and loss of workdays in healthcare workers | Communications Medicine Nature

Engineered yeast provides rare but essential pollen sterols for honeybees Nature

Optical generative models Nature

A generic non-invasive neuromotor interface for human-computer interaction Nature

New discoveries of Australopithecus and Homo from Ledi-Geraru, Ethiopia Nature

Monumental rock art illustrates that humans thrived in the Arabian Desert during the Pleistocene-Holocene transition Nature

Spouses tend to share psychiatric disorders, massive study finds Nature

Systematic attribution of heatwaves to the emissions of carbon majors Nature

Ultrabroadband on-chip photonics for full-spectrum wireless communications Nature

Analog optical computer for AI inference and combinatorial optimization Nature

DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning Nature

Flexoelectricity and surface ferroelectricity of water ice Nature

New hope for Alzheimer’s: lithium supplement reverses memory loss in mice Nature

Psilocybin treatment extends cellular lifespan and improves survival of aged mice | npj Aging Nature

Emerging evidence of abrupt changes in the Antarctic environment Nature

Scientists hide messages in papers to game AI peer review Nature

A foundation model to predict and capture human cognition Nature

Targeting iron-associated protein Ftl1 in the brain of old mice improves age-related cognitive impairment Nature

The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli Nature

Pig-to-human lung xenotransplantation into a brain-dead recipient Nature

Global hotspots of mycorrhizal fungal richness are poorly protected Nature

Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results Nature

Discovery and dynamics of a Sedna-like object with a perihelion of 66 au Nature

High diversity of dietary flavonoid intake is associated with a lower risk of all-cause mortality and major chronic diseases Nature

Energy–speed relationship of quantum particles challenges Bohmian mechanics Nature

Magnetically induced convection enhances water electrolysis in microgravity Nature

A natural experiment on the effect of herpes zoster vaccination on dementia Nature

The first emergence of unprecedented global water scarcity in the Anthropocene Nature

Land subsidence risk to infrastructure in US metropolises Nature

Mosaic anatomy in an early fossil squamate Nature

Millimetre-scale bioresorbable optoelectronic systems for electrotherapy Nature

Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease Nature

75% of US scientists who answered Nature poll consider leaving Nature

Gap between national food production and food-based dietary guidance highlights lack of national self-sufficiency Nature

Geographic and age variations in mutational processes in colorectal cancer Nature

A domed pachycephalosaur from the early Cretaceous of Mongolia Nature

Extremely stripped supernova reveals a silicon and sulfur formation site Nature

Optimal dietary patterns for healthy aging Nature

Exclusive: NSF stops awarding new grants and funding existing ones Nature

US Supreme Court allows NIH to cut $2 billion in research grants Nature

Space-time crystals from particle-like topological solitons Nature

The effect of ChatGPT on students’ learning performance, learning perception, and higher-order thinking: insights from a meta-analysis | Humanities and Social Sciences Communications Nature

Meal timing trajectories in older adults and their associations with morbidity, genetic profiles, and mortality Nature

High-income groups disproportionately contribute to climate extremes worldwide Nature

A biocompatible Lossen rearrangement in Escherichia coli Nature

Assessing and alleviating state anxiety in large language models - npj Digital Medicine Nature

Contextualizing ancient texts with generative neural networks Nature

Latest Cretaceous megaraptorid theropod dinosaur sheds light on megaraptoran evolution and palaeobiology Nature

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity Nature

Exclusive: NIH to end billions of dollars in foreign research grants Nature

Nature journal accused of abandoning science for social justice The Times

Carbon majors and the scientific case for climate liability Nature

Global phenology maps reveal the drivers and effects of seasonal asynchrony Nature

Ancient DNA from the Green Sahara reveals ancestral North African lineage Nature

Genome-wide association study of long COVID Nature

Long-range PM2.5 pollution and health impacts from the 2023 Canadian wildfires Nature

How climate change and deforestation interact in the transformation of the Amazon rainforest Nature

RFK Jr demanded a vaccine study be retracted — the journal said no Nature

A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis Nature