Gedmore B.V.

Why Gedmore? Gedmore brings PK-PD modeling to pharmaceutical research. PK-PD’s unique predictive capabilities are extensively used to support clinical decisions, but its wider implementation is hindered by the associated time and costs. Gedmore’s aim is to change this. Gedmore applies modern web technology to offer tailored PK-PD modeling at highly reduced cost and turnaround time. Research can now leverage PK-PD to accelerate decision making and improve designs, too! Overview Gedmore is a system that automates PK-PD model development. Data are entered using an easy and graphical interface. Results are delivered in a practical report format that can be directly used in presentations or other forms of communication. Gedmore is available as a web application, comparable to Software-as-a-Service (SaaS) solutions. There is no install or any license commitment needed, you only pay for what you are using. The scope of Gedmore’s initial release is the analysis of screening PK experiments. These experiments are typically conducted by dosing animals with a single dose of an investigational drug intravenously, and another group by the oral route. These data are than subjected to Gedmore’s proprietary model automation system. A combination of brute force calculations and expert-system decisions is applied to develop models. The user is presented with the end-result in terms of ready-to-use simulations in a practical report.