Gemphire is a clinical stage biopharmaceutical company focused on developing and commercializing therapies for the treatment of dyslipidemia, a serious medical condition that increases the risk of life threatening cardiovascular disease. We are developing our product candidate gemcabene (CI 1027), a novel, once daily, oral therapy, for patients who are unable to achieve normal levels of LDL C or triglycerides with currently approved therapies, primarily statin therapy. Gemcabene’s mechanism of action is designed to enhance the clearance of very low density lipoproteins (VLDLs) in the plasma and inhibit the production of fatty acids and cholesterol in the liver. The Gemphire team is also exploring the utility of gemcabene in Nonalcoholic Steatohepatitis (NASH) and/or Nonalcoholic Fatty Liver Disease (NAFLD) given its mechanism of action that decreases the production of the apoC III protein and may inhibit ACC, which has been observed to result in the lowering of triglycerides in the plasma and may reduce liver fat. We are focused on a broad spectrum of indications for dyslipidemia patients ranging from the orphan indication HoFH to more prevalent conditions, such as HeFH, ASCVD and SHTG. In the next twelve months, we plan to initiate three late stage clinical trials with early results expected starting at the end of 2016 continuing through the first half of 2018.
Company Details
- Employees
- 2
- Founded
- -
- Address
- 17199 N.laurel Park Dr.,
- Phone
- (248) 980-6538
- Industry
- Pharmaceutical Manufacturing
- NAICS
-
Pharmaceutical and Medicine ManufacturingMedicinal and Botanical ManufacturingPharmaceutical Preparation ManufacturingIn-Vitro Diagnostic Substance ManufacturingBiological Product (except Diagnostic) Manufacturing
- Website
- gemphire.com
- Keywords
- Cardiovascular and NASH.
- HQ
- Livonia, MI
Gemphire Therapeutics Questions
Gemphire Therapeutics's helpline number is (248) 980-6538
Gemphire Therapeutics's website is gemphire.com
Gemphire Therapeutics's LinkedIn profile is https://www.linkedin.com/company/gemphire-therapuetics
Gemphire Therapeutics has
2 employees.
View email and phone details for 2
employees at Gemphire Therapeutics.
Gemphire Therapeutics's industry is
Pharmaceutical Manufacturing
Gemphire Therapeutics's top competitors are
Metavia,
Sidewinder Therapeutics, Inc,
Odenn Impact Llc,
Basking Biosciences Inc,
Cormedix Inc.,
Excel Venture Management, Llc,
Nozin,
Arkayli Biopharma, Inc.,
Clinaudits, Llc,
Genome Biologics.
Gemphire Therapeutics's categories are Pharmaceutical Manufacturing
Gemphire Therapeutics's founding year is 2011
