Gene Nexus

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Gene Nexus aims to drive innovation in drug discovery through genetics- and OMICs-guided approaches and strategic planning, and provides consulting services in the following areas: 1. Bespoke target selection for emerging drug modalities 2. Genetics-driven novel target discovery and validation 3. Business development for CROs with genetics or biomedical intelligence based platforms pursuing pharma partnerships 4. Setting high-level scientific and commercial go-forward strategy for data-driven early R&D 5. Advancing diverse ancestry genomic biobanks with a focus on global health equity --- Founder and Principal Consultant: Sneha Grandhi, PhD Background: - 5 years at Pfizer's 'Emerging Science and Innovation' division, whose mission was to "Bring the Best of the Outside Into Pfizer" - Postdoctoral training at Harvard Medical School's Department of Genetics - PhD in Genetics and Genome Sciences (Case Western Reserve University) - B.S. in Genomics and Molecular Genetics, minor in Mathematics (Michigan State University) Achievements: - Led innovative projects using population genetics and OMICs data for novel target discovery - Proposed 8 first-in-class targets which entered Pfizer's discovery portfolio - Contributed to 4 successful stage gate transitions of Pfizer preclinical programs - Spearheaded 3 strategic partnerships with global biobanks and secured C-suite endorsement - Conducted pharma due diligence for 25+ biotechs, consortia, and AI/ML platforms seeking partnerships Expertise: - Disease-agnostic target discovery and validation (oncology, hematology, rare disease, inflammation, and CVD) - Diverse therapeutic modalities (small/large molecules, RNA tx, gene editing, heterobifunctional molecules / molecular glues) - Biomarker identification and patient population selection - Scientific communication and cross-functional collaboration

Company Details

Employees
1
Founded
-
Industry
Research Services
NAICS
Scientific Research and Development Services
Research and Development in the Physical, Engineering, and Life Sciences
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
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