GET-IN DN MSCA

Apply for a doctoral project and take part in GET-IN. The MCSA Doctoral Network GET-IN (the GEne Therapy INnovation Training Network) is In search of 10 Doctoral Candidates. 1) Tackling critical knowledge gaps The aim of GET-IN is to address significant knowledge gaps that currently hinder the widespread adoption of gene therapies. This involves optimization of scalable up-stream and down-stream processes, which includes enhancing the production through bioengineering and developing industry-standard biomanufacturing practices. Additionally, GET-IN aims to discover novel, safe, and efficacious gene editing tools broadly applicable, which will be combined with innovative delivery methods. GET-IN will develop cutting-edge organ-on-chip (OoC) technology that allows for the evaluation of efficacy, target tissue specificity, and toxicity in humanized models, surpassing current animal model standards. 2) Training next-generation innovators GET-IN's 10 doctoral candidates will receive extensive training in the gene therapy field, which will prepare them well for the highly competitive job market. Moreover, they will be able to contribute to ground-breaking innovations in the field of gene therapy, such as viral vector production, design of experiments, quality by design, digital twin simulation, CRISPR genome editing, and organ-on-chip engineering. The PhD projects are complementary and interconnected, and they include industrial internships and innovative training modules. The candidates become part of a broader network that comprises both academic and industrial leaders. 3) Co-creation GET-IN brings together gene therapy innovators from academia and industry. By combining cutting-edge research with industry-standard bioengineering practices, standardization, and optimization of manufacturing processes, GET-IN aims to provide practical solutions to real-world problems. Early adoption of GET-IN's innovations will help to improve market access of novel gene therapies.