Harold Grinspoon Foundation

Harold Grinspoon Foundation company information, Employees & Contact Information

Inspired by the deep meaning and joy offered by Jewish living, the Harold Grinspoon Foundation (The HGF) helps people connect to Jewish values, faith, traditions, and culture, and build vibrant Jewish communities. The HGF has several flagship programs including PJ Library, JCamp 180, Life & Legacy, Voices & Visions, and Western Mass Grants. HGF flagship initiatives focus on Jewish outreach: • PJ Library® shares Jewish culture and values through children’s books that reflect the diversity of Jewish customs and practice. This global program is made possible by thousands of generous supporters, local program partners, the PJ Library Alliance, and the Harold Grinspoon Foundation. To learn more about the program and ways to connect to local activities, visit pjlibrary.org. • PJ Library's sister program in Israel, Sifriyat Pijama, is currently serving more than 400,000 children in schools throughout Israel in partnership with the Ministry of Education. • The Voices & Visions program elicits the power of art to communicate great Jewish ideas. The project aims to inspire Jewish conversation, instill pride, and spark creativity among diverse audiences and ages • JCamp180 works to strengthen the infrastructure of Jewish camps throughout North America by providing mentor services in strategic planning, board development, fundraising, and technology • The Life & Legacy program offers an incentivized path to help communities secure meaningful after-lifetime legacy gifts for the future of their Jewish communal organizations • The Harold Grinspoon Charitable Foundation (HGCF) provides philanthropic support primarily in Western Massachusetts. Programs include the Entrepreneurship Initiative, Local Farmer Awards, Pioneer Valley Excellence in Teaching Awards, and ener-G-save.
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Macrophage Subpopulation Promotes Skeletal Muscle Regeneration Through HGF/MET Signaling-Mediated Skeletal Muscle Stem Cell Proliferation - Wiley Online Library

Macrophage Subpopulation Promotes Skeletal Muscle Regeneration Through HGF/MET Signaling-Mediated Skeletal Muscle Stem Cell Proliferation Wiley Online Library

Epithelial tubule interconnection driven by HGF-Met signaling in the kidney - PNAS

Epithelial tubule interconnection driven by HGF-Met signaling in the kidney PNAS

HGF and MET: From Brain Development to Neurological Disorders - Frontiers

HGF and MET: From Brain Development to Neurological Disorders Frontiers

Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39 - Journal of Neuroscience

Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39 Journal of Neuroscience

Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling | Circulation Research - American Heart Association Journals

Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling | Circulation Research American Heart Association Journals

Mesenchymal stem cell-derived HGF attenuates radiation-induced senescence in salivary glands via compensatory proliferation - ScienceDirect.com

Mesenchymal stem cell-derived HGF attenuates radiation-induced senescence in salivary glands via compensatory proliferation ScienceDirect.com

The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients - Nature

The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients Nature

Partnership invests $267,850 in 116 WMass farms - MassLive

Partnership invests $267,850 in 116 WMass farms MassLive

Molecular mechanism(s) of regulation(s) of c-MET/HGF signaling in head and neck cancer - Molecular Cancer

Molecular mechanism(s) of regulation(s) of c-MET/HGF signaling in head and neck cancer Molecular Cancer

Targeting the HGF/MET Axis in Cancer Therapy: Challenges in Resistance and Opportunities for Improvement - Frontiers

Targeting the HGF/MET Axis in Cancer Therapy: Challenges in Resistance and Opportunities for Improvement Frontiers

Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation - ScienceDirect.com

Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation ScienceDirect.com

Crosstalk Mechanisms Between HGF/c-Met Axis and ncRNAs in Malignancy - Frontiers

Crosstalk Mechanisms Between HGF/c-Met Axis and ncRNAs in Malignancy Frontiers

LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion - ScienceDirect.com

LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion ScienceDirect.com

The Role of Hepatocyte Growth Factor (HGF) in Insulin Resistance and Diabetes - Frontiers

The Role of Hepatocyte Growth Factor (HGF) in Insulin Resistance and Diabetes Frontiers

Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor - Frontiers

Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor Frontiers

ATH-1105, a small-molecule positive modulator of the neurotrophic HGF system, is neuroprotective, preserves neuromotor function, and extends survival in preclinical models of ALS - Frontiers

ATH-1105, a small-molecule positive modulator of the neurotrophic HGF system, is neuroprotective, preserves neuromotor function, and extends survival in preclinical models of ALS Frontiers

HGF/c-Met: A Key Promoter in Liver Regeneration - Frontiers

HGF/c-Met: A Key Promoter in Liver Regeneration Frontiers

HGF/c-Met Axis: The Advanced Development in Digestive System Cancer - Frontiers

HGF/c-Met Axis: The Advanced Development in Digestive System Cancer Frontiers

Cytokine IL-5 and HGF: combined prediction of non-/low immune response to hepatitis B vaccination at birth in infants born to HBsAg-positive mothers - Frontiers

Cytokine IL-5 and HGF: combined prediction of non-/low immune response to hepatitis B vaccination at birth in infants born to HBsAg-positive mothers Frontiers

The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma - Frontiers

The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma Frontiers

Uncertainty in perception and the Hierarchical Gaussian Filter - Frontiers

Uncertainty in perception and the Hierarchical Gaussian Filter Frontiers

HGF/c-MET pathway in cancer: from molecular characterization to clinical evidence - Nature

HGF/c-MET pathway in cancer: from molecular characterization to clinical evidence Nature

Effect of controlled release of HGF on extracellular vesicle secretion by urine-derived stem cells - Frontiers

Effect of controlled release of HGF on extracellular vesicle secretion by urine-derived stem cells Frontiers

Expression of Concern: HGF and c-Met Interaction Promotes Migration in Human Chondrosarcoma Cells - PLOS

Expression of Concern: HGF and c-Met Interaction Promotes Migration in Human Chondrosarcoma Cells PLOS

Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models - PNAS

Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models PNAS

Identifying HIF1A and HGF as two hub genes in aortic dissection and function analysis by integrating RNA sequencing and single-cell RNA sequencing data - Frontiers

Identifying HIF1A and HGF as two hub genes in aortic dissection and function analysis by integrating RNA sequencing and single-cell RNA sequencing data Frontiers

HGF-mediated elevation of ETV1 facilitates hepatocellular carcinoma metastasis through upregulating PTK2 and c-MET - Journal of Experimental & Clinical Cancer Research

HGF-mediated elevation of ETV1 facilitates hepatocellular carcinoma metastasis through upregulating PTK2 and c-MET Journal of Experimental & Clinical Cancer Research

Treatment of Polarized Cystic Fibrosis Airway Cells With HGF Prevents VX-661-Rescued F508del-CFTR Destabilization Caused by Prolonged Co-exposure to VX-770 - Frontiers

Treatment of Polarized Cystic Fibrosis Airway Cells With HGF Prevents VX-661-Rescued F508del-CFTR Destabilization Caused by Prolonged Co-exposure to VX-770 Frontiers

Reduced HGF/MET Signaling May Contribute to the Synaptic Pathology in an Alzheimer's Disease Mouse Model - Frontiers

Reduced HGF/MET Signaling May Contribute to the Synaptic Pathology in an Alzheimer's Disease Mouse Model Frontiers

Prolonged co-treatment with HGF sustains epithelial integrity and improves pharmacological rescue of Phe508del-CFTR - Nature

Prolonged co-treatment with HGF sustains epithelial integrity and improves pharmacological rescue of Phe508del-CFTR Nature

HGF/c-Met signaling promotes the migration and proliferation of deer antler MSCs - Nature

HGF/c-Met signaling promotes the migration and proliferation of deer antler MSCs Nature

Molecular mechanism study of HGF/c-MET pathway activation and immune regulation for a tumor diagnosis model - Cancer Cell International

Molecular mechanism study of HGF/c-MET pathway activation and immune regulation for a tumor diagnosis model Cancer Cell International

Structural basis of the activation of c-MET receptor - Nature

Structural basis of the activation of c-MET receptor Nature

HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression - Frontiers

HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression Frontiers

M2 macrophages mediate sorafenib resistance by secreting HGF in a feed-forward manner in hepatocellular carcinoma - Nature

M2 macrophages mediate sorafenib resistance by secreting HGF in a feed-forward manner in hepatocellular carcinoma Nature

Collagen-Binding Hepatocyte Growth Factor (HGF) alone or with a Gelatin- furfurylamine Hydrogel Enhances Functional Recovery in Mice after Spinal Cord Injury - Nature

Collagen-Binding Hepatocyte Growth Factor (HGF) alone or with a Gelatin- furfurylamine Hydrogel Enhances Functional Recovery in Mice after Spinal Cord Injury Nature

Metformin reduces HGF-induced resistance to alectinib via the inhibition of Gab1 - Nature

Metformin reduces HGF-induced resistance to alectinib via the inhibition of Gab1 Nature

The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing - Nature

The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing Nature

HGF-mediated crosstalk between cancer-associated fibroblasts and MET -unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis - Nature

HGF-mediated crosstalk between cancer-associated fibroblasts and MET -unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis Nature

Fibroadipogenic Progenitors Regulate the Basal Proliferation of Satellite Cells and Homeostasis of Pharyngeal Muscles via HGF Secretion - Frontiers

Fibroadipogenic Progenitors Regulate the Basal Proliferation of Satellite Cells and Homeostasis of Pharyngeal Muscles via HGF Secretion Frontiers

An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides - Nature

An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides Nature

The Emerging Role of the c-MET-HGF Axis in Non-small Cell Lung Cancer Tumor Immunology and Immunotherapy - Frontiers

The Emerging Role of the c-MET-HGF Axis in Non-small Cell Lung Cancer Tumor Immunology and Immunotherapy Frontiers

Deciphering treatment resistance in metastatic colorectal cancer: roles of drug transports, EGFR mutations, and HGF/c-MET signaling - Frontiers

Deciphering treatment resistance in metastatic colorectal cancer: roles of drug transports, EGFR mutations, and HGF/c-MET signaling Frontiers

Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP - Nature

Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP Nature

HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis - Nature

HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis Nature

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion - Nature

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion Nature

Children’s books light up Arabian nights - Unpacked

Children’s books light up Arabian nights Unpacked

Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice - Nature

Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice Nature

NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair | Cell Death & Disease - Nature

NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair | Cell Death & Disease Nature

Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling - Stem Cell Research & Therapy

Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling Stem Cell Research & Therapy

Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway - Nature

Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway Nature

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM - PNAS

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM PNAS

Overexpression of HGF Retards Disease Progression and Prolongs Life Span in a Transgenic Mouse Model of ALS - Journal of Neuroscience

Overexpression of HGF Retards Disease Progression and Prolongs Life Span in a Transgenic Mouse Model of ALS Journal of Neuroscience

Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis - Nature

Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis Nature

Inhibition of hypoxia/reoxygenation-induced oxidative stress in HGF-stimulated antiapoptotic signaling: role of PI3-K and Akt kinase upon rac1 - Nature

Inhibition of hypoxia/reoxygenation-induced oxidative stress in HGF-stimulated antiapoptotic signaling: role of PI3-K and Akt kinase upon rac1 Nature

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway - Nature

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway Nature

RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. - EMBO Press

RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. EMBO Press

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