Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Helmholtz Institute For Pharmaceutical Research Saarland (Hips) company information, Employees & Contact Information

The Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) was established in 2009 as a joint venture of the Helmholtz Centre for Infection Research (HZI) and Saarland University. Located on the Saarbrücken campus, we are Germany’s first research institute dedicated explicitly to pharmaceutical research, driving innovative solutions to combat infectious diseases. Our work focuses on the development of novel anti-infectives and their optimization for clinical application – with a clear translational approach. We integrate cutting-edge strategies in synthetic and natural product-based drug discovery with advanced methods in bioinformatics and drug delivery. Our mission: to create new therapies and strategies to tackle antibiotic resistance and other global challenges in infectious diseases. Supported by an interdisciplinary and international team, we are advancing research for a healthier future.
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Value Addition to African Natural Product-Based Drug Discovery Initiatives - ACS Publications

Value Addition to African Natural Product-Based Drug Discovery Initiatives ACS Publications

Double Funding for HIPS Junior Researchers - Helmholtz-Zentrum für Infektionsforschung

Double Funding for HIPS Junior Researchers Helmholtz-Zentrum für Infektionsforschung

In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens - ACS Publications

In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens ACS Publications

BioVersys AG and Helmholtz Centre for Infection Research join forces to accelerate AMR research and development - Deutsches Zentrum für Infektionsforschung

BioVersys AG and Helmholtz Centre for Infection Research join forces to accelerate AMR research and development Deutsches Zentrum für Infektionsforschung

A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro - Frontiers

A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro Frontiers

"AI will be a gamechanger in antibiotics research" - Helmholtz - Association of German Research Centres - Helmholtz-Gemeinschaft Deutscher Forschungszentren

"AI will be a gamechanger in antibiotics research" - Helmholtz - Association of German Research Centres Helmholtz-Gemeinschaft Deutscher Forschungszentren

Molecular replacement for small-molecule crystal structure determination from X-ray and electron diffraction data with reduced resolution - Wiley Online Library

Molecular replacement for small-molecule crystal structure determination from X-ray and electron diffraction data with reduced resolution Wiley Online Library

Searching for the microbial treasure - Helmholtz-Zentrum für Infektionsforschung

Searching for the microbial treasure Helmholtz-Zentrum für Infektionsforschung

Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles - ACS Publications

Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles ACS Publications

Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms - Frontiers

Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms Frontiers

Drug Discovery within the Patient - Helmholtz-Zentrum für Infektionsforschung

Drug Discovery within the Patient Helmholtz-Zentrum für Infektionsforschung

Uncovering a Subtype of Microviridins via the Biosynthesis Study of FR901451 - ACS Publications

Uncovering a Subtype of Microviridins via the Biosynthesis Study of FR901451 ACS Publications

Award for outstanding achievements in natural product research - Helmholtz-Zentrum für Infektionsforschung

Award for outstanding achievements in natural product research Helmholtz-Zentrum für Infektionsforschung

New Genetically Engineered Derivatives of Antibacterial Darobactins Underpin Their Potential for Antibiotic Development - ACS Publications

New Genetically Engineered Derivatives of Antibacterial Darobactins Underpin Their Potential for Antibiotic Development ACS Publications

10 years of pharmaceutical research at the HIPS - Helmholtz-Zentrum für Infektionsforschung

10 years of pharmaceutical research at the HIPS Helmholtz-Zentrum für Infektionsforschung

Engineering Atypical Tetracycline Formation in Amycolatopsis sulphurea for the Production of Modified Chelocardin Antibiotics - ACS Publications

Engineering Atypical Tetracycline Formation in Amycolatopsis sulphurea for the Production of Modified Chelocardin Antibiotics ACS Publications

Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity - ACS Publications

Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity ACS Publications

Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases - ACS Publications

Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases ACS Publications

Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections - ACS Publications

Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections ACS Publications

Analysis of diffuse scattering in electron diffraction data for the crystal structure determination of Pigment Orange 13, C - Wiley Online Library

Analysis of diffuse scattering in electron diffraction data for the crystal structure determination of Pigment Orange 13, C Wiley Online Library

A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms - Wiley Online Library

A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms Wiley Online Library

A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms - Wiley Online Library

A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms Wiley Online Library

Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa | ACS Infectious Diseases - ACS Publications

Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa | ACS Infectious Diseases ACS Publications

Discovery of Small-Molecule Stabilizers of 14-3-3 Protein–Protein Interactions via Dynamic Combinatorial Chemistry - ACS Publications

Discovery of Small-Molecule Stabilizers of 14-3-3 Protein–Protein Interactions via Dynamic Combinatorial Chemistry ACS Publications

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