HitChem integrates advanced cheminformatics and cutting-edge language models to accelerate early-stage small molecule drug discovery. Our proprietary platform combines AI-driven molecule design with ultra-high-throughput screening to speed up hit identification and lead generation.
What We Can Offer:
Small Molecular Library Collections
- Diversity Library: 53,359 compounds picked by experienced chemists from 26 million commercial compounds, offering broad coverage of chemical space with diverse scaffolds.
- CRBN-Focused Molecular Glues library: 18,000 in-house designed compounds equipped with validated CRBN-binding warheads. Approximately 40% compounds in the library demonstrate confirmed binary binding to CRBN, offering significantly higher hit rates in later ternary assays.
- Cyclic Peptide Library: A unique collection of cyclic peptides ranging from 5 to 10 amino acids in length with both sequence and physicochemical properties diversity.
- Sp³-enriched library: 14,000 compounds with Sp3-rich scaffolds for enhanced molecular diversity. These relatively rigid compounds are particularly suitable for CNS-target screening.
- Covalent Library: A collection of diverse and Sp3-rich covalent compounds with the most demanded warhead types.
2D Molecular Generation Model: Our molecular generation model enables rapid exploration of chemical space based on your input fragment or scaffold. Whether you’re optimizing a hit compound or seeking novel scaffolds, our 2DMG tool can generates diverse, drug-like structures to help on your project goals.
Integrative chemistry services: We offer end-to-end chemistry support from hit identification to lead optimization, including: High-Throughput Virtual Screening (HTVS), Structure–Activity Relationship (SAR) Analysis, Computer-Aided Drug Design (CADD), Hit Similarity Searching etc.
Contact Us: marketing@hit-chem.com
Company Details
- Employees
- 2
- Founded
- -
- Address
- San Francisco, Ca, Us
- Industry
- Biotechnology Research
- NAICS
-
Research and Development in Biotechnology (except Nanobiotechnology)
- Website
- https://www.hit-chem.com/
- Keywords
- Small Molecular Design and Optimization, Computational Chemistry, Small Molecule Libraries, 2D/3D Generative Model, High Throughput Virtual Screening, Hit Finding and Identification, Molecular Glue Library, Diverse Compound Library, cyclic peptide library.
- HQ
- San Francisco, CA
Hitchem Questions
Hitchem's website is https://www.hit-chem.com/
Hitchem's LinkedIn profile is https://www.linkedin.com/company/hitchem
Hitchem has
2 employees.
View email and phone details for 2
employees at Hitchem.
Hitchem's industry is
Biotechnology Research
Hitchem's top competitors are
J-Star Research, Inc.,
Porton Pharma Solutions Ltd.,
Offnest Inc.,
Atombeat Inc.,
Careerengineus,
Stonewise,
Genesis Therapeutics,
北京望石智慧科技有限公司,
Innostar,
Ice Bioscience.
Hitchem's categories are Biotechnology Research
Hitchem's founding year is 2018
