Botnar Institute Of Immune Engineering – Biie

Botnar Institute Of Immune Engineering – Biie company information, Employees & Contact Information

The Botnar Institute of Immune Engineering (BIIE) is a non-profit research organisation focused on the advanced study of immunological systems with a mission to develop translational solutions for the diagnosis, treatment and prevention of disease. With this focus, the BIIE is committed to advancing global child and adolescent health. Outstanding investigators from around the globe will be recruited to its facility in Basel, Switzerland, to form a new hub of innovation in immune engineering. The Institute's mission is to harness the potential of immune engineering to enhance the lives of children and young people globally, and to deliver on the promise of a healthier future. The BIIE is made possible by the generous endowment of over 1 Billion USD to be provided over 15 years from Fondation Botnar, a Swiss philanthropic foundation working to improve the health and wellbeing of young people around the world.

Company Details

Employees
37
Founded
-
Address
Basel, Ch
Industry
Research Services
NAICS
Scientific Research and Development Services
Research and Development in the Physical, Engineering, and Life Sciences
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
HQ
Basel
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News

Faculty Positions in Immune Engineering and Cellular Therapies - Nature

Faculty Positions in Immune Engineering and Cellular Therapies Nature

Fc engineering and the antibody immune code - News-Medical

Fc engineering and the antibody immune code News-Medical

Charles Park named 2025 STAT Wunderkind - Wyss Institute at Harvard

Charles Park named 2025 STAT Wunderkind Wyss Institute at Harvard

CAR T Cells: Engineering Patients’ Immune Cells to Treat Their Cancers - National Cancer Institute (.gov)

CAR T Cells: Engineering Patients’ Immune Cells to Treat Their Cancers National Cancer Institute (.gov)

Systematic discovery and engineering of synthetic immune receptors in plants - Science | AAAS

Systematic discovery and engineering of synthetic immune receptors in plants Science | AAAS

Engineering immune cells within the body - National Institutes of Health (.gov)

Engineering immune cells within the body National Institutes of Health (.gov)

Immune-evasive beta cells in type 1 diabetes: innovations in genetic engineering, biomaterials, and computational modeling - Frontiers

Immune-evasive beta cells in type 1 diabetes: innovations in genetic engineering, biomaterials, and computational modeling Frontiers

Biomaterial scaffolds for therapeutic immune cell engineering and delivery - ScienceDirect.com

Biomaterial scaffolds for therapeutic immune cell engineering and delivery ScienceDirect.com

Engineering Escherichia coli Nissle 1917 Carrying PD1 Agonists Resolves Intestinal Inflammation via Local Immune Modulation - ACS Publications

Engineering Escherichia coli Nissle 1917 Carrying PD1 Agonists Resolves Intestinal Inflammation via Local Immune Modulation ACS Publications

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy - Wiley

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy Wiley

MIT and Harvard Build “Invisible” Immune Cells That Obliterate Cancer - SciTechDaily

MIT and Harvard Build “Invisible” Immune Cells That Obliterate Cancer SciTechDaily

Immune cell engineering for cancer therapy 2026 - Nature

Immune cell engineering for cancer therapy 2026 Nature

Engineering innate immune cells for cancer immunotherapy - Nature

Engineering innate immune cells for cancer immunotherapy Nature

Single atom engineering for radiotherapy-activated immune agonist prodrugs - Nature

Single atom engineering for radiotherapy-activated immune agonist prodrugs Nature

About this Collection | Immune cell engineering for cancer therapy 2026 - Nature

About this Collection | Immune cell engineering for cancer therapy 2026 Nature

Boosting immune cells to combat cancer using CRISPR engineering and large-scale in vivo testing - Nature

Boosting immune cells to combat cancer using CRISPR engineering and large-scale in vivo testing Nature

An immune-competent lung-on-a-chip for modelling the human severe influenza infection response - Nature

An immune-competent lung-on-a-chip for modelling the human severe influenza infection response Nature

Engineering STING Nanoadjuvants for spatiotemporally-tailored innate immunity stimulation and cancer vaccination therapy - Nature

Engineering STING Nanoadjuvants for spatiotemporally-tailored innate immunity stimulation and cancer vaccination therapy Nature

Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles to establish T-cell tolerance - Nature

Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles to establish T-cell tolerance Nature

Toward recreating the brain’s immune system in a dish - Wyss Institute at Harvard

Toward recreating the brain’s immune system in a dish Wyss Institute at Harvard

Engineering the physical characteristics of biomaterials for innate immune-mediated cancer immunotherapy - ScienceDirect.com

Engineering the physical characteristics of biomaterials for innate immune-mediated cancer immunotherapy ScienceDirect.com

Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering - Nature

Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering Nature

Ligand engineering-mediated plasma/supramolecular self-assembly of superstructures sensitized dual immune checkpoint biosensors - ScienceDirect.com

Ligand engineering-mediated plasma/supramolecular self-assembly of superstructures sensitized dual immune checkpoint biosensors ScienceDirect.com

Multimodal chitosan-based materials for combination immunotherapy in cancers: Structural engineering, immune regulatory mechanisms and synergistic therapeutic applications - ScienceDirect.com

Multimodal chitosan-based materials for combination immunotherapy in cancers: Structural engineering, immune regulatory mechanisms and synergistic therapeutic applications ScienceDirect.com

Engineering the immune and fibrotic response in VML - Wiley

Engineering the immune and fibrotic response in VML Wiley

Engineering Immune Responses: Protein Design for the Next Era of Cancer Therapy - Technology Networks

Engineering Immune Responses: Protein Design for the Next Era of Cancer Therapy Technology Networks

Stattic engineering M2 macrophage-derived exosomes mediate autophagy and immune reprogramming for secondary hyperparathyroidism - ScienceDirect.com

Stattic engineering M2 macrophage-derived exosomes mediate autophagy and immune reprogramming for secondary hyperparathyroidism ScienceDirect.com

Researchers crack the code of body’s ancient immune defense - Penn Engineering Blog

Researchers crack the code of body’s ancient immune defense Penn Engineering Blog

Laurel Hind honored with CAREER Award for advancing immune response research - University of Colorado Boulder

Laurel Hind honored with CAREER Award for advancing immune response research University of Colorado Boulder

A gut-on-a-chip incorporating human faecal samples and peristalsis predicts responses to immune checkpoint inhibitors for melanoma - Nature

A gut-on-a-chip incorporating human faecal samples and peristalsis predicts responses to immune checkpoint inhibitors for melanoma Nature

FAMU-FSU College of Engineering researchers create innovative microparticles that unlock new insights into protein degradation and immune cell behavior - Florida State University

FAMU-FSU College of Engineering researchers create innovative microparticles that unlock new insights into protein degradation and immune cell behavior Florida State University

Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells - Nature

Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells Nature

Engineering a Self-Delivery Nanoplatform for Chemo-Photodynamic-Immune Synergistic Therapies against Aggressive Melanoma - ACS Publications

Engineering a Self-Delivery Nanoplatform for Chemo-Photodynamic-Immune Synergistic Therapies against Aggressive Melanoma ACS Publications

Non-viral, high throughput genetic engineering of primary immune cells using nanostraw-mediated transfection - ScienceDirect.com

Non-viral, high throughput genetic engineering of primary immune cells using nanostraw-mediated transfection ScienceDirect.com

Biopharma in Basel builds amid global correction - R&D World

Biopharma in Basel builds amid global correction R&D World

Tracking immune cell brain cancer therapies with ultrasound - Penn State University

Tracking immune cell brain cancer therapies with ultrasound Penn State University

Efficient non-viral immune cell engineering using circular single-stranded DNA-mediated genomic integration - Nature

Efficient non-viral immune cell engineering using circular single-stranded DNA-mediated genomic integration Nature

AI-Enhanced Zinc Finger Proteins May Reduce Immune Risks in Cell and Gene Therapies - Genetic Engineering and Biotechnology News

AI-Enhanced Zinc Finger Proteins May Reduce Immune Risks in Cell and Gene Therapies Genetic Engineering and Biotechnology News

Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells - ScienceDirect.com

Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells ScienceDirect.com

Immune Cell Engineering Market to Hit USD 17.51 Bn by 2032, Registering 22.5% CAGR – Coherent Market Insights - BioSpace

Immune Cell Engineering Market to Hit USD 17.51 Bn by 2032, Registering 22.5% CAGR – Coherent Market Insights BioSpace

Hydrogel systems for spatiotemporal controlled delivery of immunomodulators: engineering the tumor immune microenvironment for enhanced cancer immunotherapy - Frontiers

Hydrogel systems for spatiotemporal controlled delivery of immunomodulators: engineering the tumor immune microenvironment for enhanced cancer immunotherapy Frontiers

A Scalable Method for Engineering Therapeutic Immune Cells - King's College London

A Scalable Method for Engineering Therapeutic Immune Cells King's College London

In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy - Nature

In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy Nature

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools - Frontiers

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools Frontiers

Immune cell engineering for cancer therapy 2024 - Nature

Immune cell engineering for cancer therapy 2024 Nature

New Swiss research institute to pioneer immune engineering and global child health - News-Medical

New Swiss research institute to pioneer immune engineering and global child health News-Medical

Aerosol pulmonary immune engineering - ScienceDirect.com

Aerosol pulmonary immune engineering ScienceDirect.com

Researchers Develop Antigen-Mimicking Synthetic Cells to Improve T-Cell Activation - UCLA Samueli School of Engineering

Researchers Develop Antigen-Mimicking Synthetic Cells to Improve T-Cell Activation UCLA Samueli School of Engineering

NYU Launches New Cross-Institutional Initiative to Advance Engineering and Health - NYU

NYU Launches New Cross-Institutional Initiative to Advance Engineering and Health NYU

U of T Engineering researchers are designing synthetic immune complexes using DNA nanotechnology - U of T Engineering News -

U of T Engineering researchers are designing synthetic immune complexes using DNA nanotechnology U of T Engineering News -

Wyss Institute’s iNodes team receives ARPA-H Sprint for Women’s Health award to advance the first implantable immune organs to treat ovarian cancer - Wyss Institute at Harvard

Wyss Institute’s iNodes team receives ARPA-H Sprint for Women’s Health award to advance the first implantable immune organs to treat ovarian cancer Wyss Institute at Harvard

Electrospun fiber‐based immune engineering in regenerative medicine - Xu - 2024 - Smart Medicine - Wiley Online Library

Electrospun fiber‐based immune engineering in regenerative medicine - Xu - 2024 - Smart Medicine Wiley Online Library

Engineering the immune system to tackle solid tumors - Penn Medicine

Engineering the immune system to tackle solid tumors Penn Medicine

In vivo engineering chimeric antigen receptor immune cells with emerging nanotechnologies - ScienceDirect.com

In vivo engineering chimeric antigen receptor immune cells with emerging nanotechnologies ScienceDirect.com

Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles - ACS Publications

Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles ACS Publications

Advancements in Targeted Therapeutics: Integrating Metabolic Modulation, Immune Engineering, and Biologic Formulation Technologies - ACS Publications

Advancements in Targeted Therapeutics: Integrating Metabolic Modulation, Immune Engineering, and Biologic Formulation Technologies ACS Publications

Polymeric materials for immune engineering: Molecular interaction to biomaterial design - ScienceDirect.com

Polymeric materials for immune engineering: Molecular interaction to biomaterial design ScienceDirect.com

Engineering immune-evasive allogeneic cellular immunotherapies - Nature

Engineering immune-evasive allogeneic cellular immunotherapies Nature

Engineering metabolism to modulate immunity - ScienceDirect.com

Engineering metabolism to modulate immunity ScienceDirect.com

Engineering human immune organoids for translational immunology - ScienceDirect.com

Engineering human immune organoids for translational immunology ScienceDirect.com

In vivo gene delivery to immune cells - ScienceDirect.com

In vivo gene delivery to immune cells ScienceDirect.com

Immune and Genome Engineering as the Future of Transplantable Tissue - The New England Journal of Medicine

Immune and Genome Engineering as the Future of Transplantable Tissue The New England Journal of Medicine

Advancements in Targeted Therapeutics: Integrating Metabolic Modulation, Immune Engineering, and Biologic Formulation Technologies - ACS Publications

Advancements in Targeted Therapeutics: Integrating Metabolic Modulation, Immune Engineering, and Biologic Formulation Technologies ACS Publications

In situ tumor cell engineering reverses immune escape to enhance immunotherapy effect - ScienceDirect.com

In situ tumor cell engineering reverses immune escape to enhance immunotherapy effect ScienceDirect.com

In vivo engineering chimeric antigen receptor immune cells with emerging nanotechnologies - ScienceDirect.com

In vivo engineering chimeric antigen receptor immune cells with emerging nanotechnologies ScienceDirect.com

Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells - Nature

Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells Nature

Multiscale engineering of immune cells and lymphoid organs - Nature

Multiscale engineering of immune cells and lymphoid organs Nature

Hydrogels for Engineering the Immune System - Li - 2021 - Advanced NanoBiomed Research - Wiley Online Library

Hydrogels for Engineering the Immune System - Li - 2021 - Advanced NanoBiomed Research Wiley Online Library

Immune-Inflammatory Responses of an Acellular Cartilage Matrix Biomimetic Scaffold in a Xenotransplantation Goat Model for Cartilage Tissue Engineering - Frontiers

Immune-Inflammatory Responses of an Acellular Cartilage Matrix Biomimetic Scaffold in a Xenotransplantation Goat Model for Cartilage Tissue Engineering Frontiers

Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity - Nature

Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity Nature

Chemical engineering meets cancer immunotherapy - MIT News

Chemical engineering meets cancer immunotherapy MIT News

Interplay between biomaterials and the immune system: Challenges and opportunities in regenerative medicine - ScienceDirect.com

Interplay between biomaterials and the immune system: Challenges and opportunities in regenerative medicine ScienceDirect.com

Modifying immune responses to adeno-associated virus vectors by capsid engineering - ScienceDirect.com

Modifying immune responses to adeno-associated virus vectors by capsid engineering ScienceDirect.com

Graft Engineering and Adoptive Immunotherapy: New Approaches to Promote Immune Tolerance After Hematopoietic Stem Cell Transplantation - Frontiers

Graft Engineering and Adoptive Immunotherapy: New Approaches to Promote Immune Tolerance After Hematopoietic Stem Cell Transplantation Frontiers

Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses - Nature

Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses Nature

M Cells: Intelligent Engineering of Mucosal Immune Surveillance - Frontiers

M Cells: Intelligent Engineering of Mucosal Immune Surveillance Frontiers

Immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive long term in allogeneic hosts - Nature

Immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive long term in allogeneic hosts Nature

Engineering approaches for studying immune-tumor cell interactions and immunotherapy - ScienceDirect.com

Engineering approaches for studying immune-tumor cell interactions and immunotherapy ScienceDirect.com

Development of NK cell-based cancer immunotherapies through receptor engineering - Nature

Development of NK cell-based cancer immunotherapies through receptor engineering Nature

Unlocking the potential of iPSC-derived immune cells: engineering iNK and iT cells for cutting-edge immunotherapy - Frontiers

Unlocking the potential of iPSC-derived immune cells: engineering iNK and iT cells for cutting-edge immunotherapy Frontiers

The future of engineered immune cell therapies - Science | AAAS

The future of engineered immune cell therapies Science | AAAS

Overcoming immune hurdles to implant longevity - Nature

Overcoming immune hurdles to implant longevity Nature

Genetic Engineering Hides Donor Organs from Host Immune System - the-scientist.com

Genetic Engineering Hides Donor Organs from Host Immune System the-scientist.com

The immune microenvironment and tissue engineering strategies for spinal cord regeneration - Frontiers

The immune microenvironment and tissue engineering strategies for spinal cord regeneration Frontiers

The application of mechanobiotechnology for immuno-engineering and cancer immunotherapy - Frontiers

The application of mechanobiotechnology for immuno-engineering and cancer immunotherapy Frontiers

Engineering in vitro immune-competent tissue models for testing and evaluation of therapeutics - ScienceDirect.com

Engineering in vitro immune-competent tissue models for testing and evaluation of therapeutics ScienceDirect.com

Engineering Biomaterials to Model Immune‐Tumor Interactions In Vitro - Wiley

Engineering Biomaterials to Model Immune‐Tumor Interactions In Vitro Wiley

Engineering antiviral immune-like systems for autonomous virus detection and inhibition in mice - Nature

Engineering antiviral immune-like systems for autonomous virus detection and inhibition in mice Nature

Immune Assisted Tissue Engineering via Incorporation of Macrophages in Cell-Laden Hydrogels Under Cytokine Stimulation - Frontiers

Immune Assisted Tissue Engineering via Incorporation of Macrophages in Cell-Laden Hydrogels Under Cytokine Stimulation Frontiers

Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector - PNAS

Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector PNAS

Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I - ScienceDirect.com

Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I ScienceDirect.com

Engineering advanced logic and distributed computing in human CAR immune cells - Nature

Engineering advanced logic and distributed computing in human CAR immune cells Nature

Engineering metabolism to modulate immunity - ScienceDirect.com

Engineering metabolism to modulate immunity ScienceDirect.com

Advances in CAR-Engineered Immune Cell Generation: Engineering Approaches and Sourcing Strategies - Wiley Online Library

Advances in CAR-Engineered Immune Cell Generation: Engineering Approaches and Sourcing Strategies Wiley Online Library

Expanding a lymph node, boosting a vaccine - Wyss Institute at Harvard

Expanding a lymph node, boosting a vaccine Wyss Institute at Harvard

Unveiling the Dynamics of Maternal Immune Responses - The University of Virginia

Unveiling the Dynamics of Maternal Immune Responses The University of Virginia

Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d - Nature

Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d Nature

i3 Center: Biomaterials to Create T Cell Immunity - Wyss Institute at Harvard

i3 Center: Biomaterials to Create T Cell Immunity Wyss Institute at Harvard

Engineering Immune Cells for in vivo Secretion of Tumor-Specific T Cell-Redirecting Bispecific Antibodies - Frontiers

Engineering Immune Cells for in vivo Secretion of Tumor-Specific T Cell-Redirecting Bispecific Antibodies Frontiers

Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes - Frontiers

Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes Frontiers

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