Immuni T

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Immuni T is a CRO company, specialises in services for biotherapeutics and immunomodulators at very competitive rates. It has expertise in customized cell-based assays, flow cytometry and ELISA assays in bioanalysis in GLP/GCLP regulated laboratories. We have developed an ex vivo method for assessing the immunogenic potential of new biotherapeutics and biosimilars, an assay performed in freshly-collected PBMC from a number of donors. This assay, for example, could assist you in the selection of the less immunogenic lead from a set of variants or to compare the immunogenic profile of a biosimilar to that of its originator. It is a rapid and cost-effective means for the evaluation of the immunogenic potential of a molecule in a human system. We perform the development and validation of immunogenicity methods and of ligand-binding assays for PK analysis for pre-clinical and clinical programs. We developed functional customized cell-based assays such as cytotoxicity assays (e.g. ADCC, CDC, in PBMC, sub-cell compartments or whole blood) and other assays such as Treg or NK functional assays. Overall, Immuni T performs cell-based assays, human ex-vivo immunogenicity prediction/comparison assays for new biotherapeutics as well as immunogenicity tests for biotherapeutics in clinical development; ligand-binding assays for the quantification/detection of peptides, proteins or nucleic acids; immuno assays based on flow cytometry analysis for determination of cell function and molecules quantification; multiplex analysis on Luminex as well as customization, development and validation of assays for pre-clinical (in GLP-compliant environment) and clinical studies.
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Chirality-protected extreme asymmetric acoustic information transport with noise immunity - Nature

Chirality-protected extreme asymmetric acoustic information transport with noise immunity Nature

Sleep & Immunity: Can a Lack of Sleep Make You Sick? - Sleep Foundation

Sleep & Immunity: Can a Lack of Sleep Make You Sick? Sleep Foundation

Ghislaine Maxwell received limited immunity during meetings with deputy attorney general: Sources - ABC News - Breaking News, Latest News and Videos

Ghislaine Maxwell received limited immunity during meetings with deputy attorney general: Sources ABC News - Breaking News, Latest News and Videos

STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity - Nature

STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity Nature

I Boost Immunity - BC Centre for Disease Control

I Boost Immunity BC Centre for Disease Control

Understanding Early-Life Adaptive Immunity to Guide Interventions for Pediatric Health - Frontiers

Understanding Early-Life Adaptive Immunity to Guide Interventions for Pediatric Health Frontiers

"Immunity passports" in the context of COVID-19 - World Health Organization (WHO)

"Immunity passports" in the context of COVID-19 World Health Organization (WHO)

Key facts from the Supreme Court’s immunity ruling and how it affects presidential power - PBS

Key facts from the Supreme Court’s immunity ruling and how it affects presidential power PBS

How Does Aging Affect Innate Immunity? - Yale School of Medicine

How Does Aging Affect Innate Immunity? Yale School of Medicine

Your Immune System: What You Need To Know - Cleveland Clinic

Your Immune System: What You Need To Know Cleveland Clinic

Nutrition and Immunity - The Nutrition Source

Nutrition and Immunity The Nutrition Source

Humoral Innate Immunity and Acute-Phase Proteins - The New England Journal of Medicine

Humoral Innate Immunity and Acute-Phase Proteins The New England Journal of Medicine

Transforming the understanding of brain immunity - Science | AAAS

Transforming the understanding of brain immunity Science | AAAS

A four-part guide to lung immunology: Invasion, inflammation, immunity, and intervention - Frontiers

A four-part guide to lung immunology: Invasion, inflammation, immunity, and intervention Frontiers

Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 - The New England Journal of Medicine

Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 The New England Journal of Medicine

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma - Nature

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma Nature

STATs in cancer inflammation and immunity: a leading role for STAT3 - Nature

STATs in cancer inflammation and immunity: a leading role for STAT3 Nature

Long-term cellular immunity of vaccines for Zaire Ebola Virus Diseases - Nature

Long-term cellular immunity of vaccines for Zaire Ebola Virus Diseases Nature

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity - Nature

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity Nature

Low-avidity T cells drive endogenous tumor immunity in mice and humans - Nature

Low-avidity T cells drive endogenous tumor immunity in mice and humans Nature

COVID-19 Story Tip: Herd Immunity Is a Dangerous Strategy for Fighting COVID-19, Says Johns Hopkins Expert - Johns Hopkins Medicine

COVID-19 Story Tip: Herd Immunity Is a Dangerous Strategy for Fighting COVID-19, Says Johns Hopkins Expert Johns Hopkins Medicine

Exploiting innate immunity for cancer immunotherapy - Molecular Cancer

Exploiting innate immunity for cancer immunotherapy Molecular Cancer

Institute for Immunity, Transplantation and Infection - Stanford Medicine

Institute for Immunity, Transplantation and Infection Stanford Medicine

Defining trained immunity and its role in health and disease - Nature

Defining trained immunity and its role in health and disease Nature

Qualified Immunity - National Conference of State Legislatures

Qualified Immunity National Conference of State Legislatures

Interim statement on hybrid immunity and increasing population seroprevalence rates - World Health Organization (WHO)

Interim statement on hybrid immunity and increasing population seroprevalence rates World Health Organization (WHO)

Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity - ScienceDirect.com

Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity ScienceDirect.com

Multifaceted mitochondria in innate immunity - Nature

Multifaceted mitochondria in innate immunity Nature

Science & Tech Spotlight: Herd Immunity For COVID-19 | U.S. GAO - U.S. Government Accountability Office (GAO) (.gov)

Science & Tech Spotlight: Herd Immunity For COVID-19 | U.S. GAO U.S. Government Accountability Office (GAO) (.gov)

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations - Frontiers

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations Frontiers

Phytoncides and immunity from forest to facility: A systematic review and meta-analysis - ScienceDirect.com

Phytoncides and immunity from forest to facility: A systematic review and meta-analysis ScienceDirect.com

Dendritic cell migration in inflammation and immunity - Nature

Dendritic cell migration in inflammation and immunity Nature

Immunity and Inflammation in Atherosclerosis | Circulation Research - American Heart Association Journals

Immunity and Inflammation in Atherosclerosis | Circulation Research American Heart Association Journals

A guide to vaccinology: from basic principles to new developments - Nature

A guide to vaccinology: from basic principles to new developments Nature

Justices rule Trump has some immunity from prosecution - SCOTUSblog

Justices rule Trump has some immunity from prosecution SCOTUSblog

Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front - ScienceDirect.com

Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front ScienceDirect.com

Wnt inhibition alleviates resistance to anti-PD1 therapy and improves antitumor immunity in glioblastoma - PNAS

Wnt inhibition alleviates resistance to anti-PD1 therapy and improves antitumor immunity in glioblastoma PNAS

Supreme Court gives win to Trump, ruling he has immunity for some acts in election interference indictment - NBC News

Supreme Court gives win to Trump, ruling he has immunity for some acts in election interference indictment NBC News

Rethinking Herd Immunity and the Covid-19 Response End Game - Johns Hopkins Bloomberg School of Public Health

Rethinking Herd Immunity and the Covid-19 Response End Game Johns Hopkins Bloomberg School of Public Health

Schumer introduces ‘No Kings Act’ in response to Supreme Court’s presidential immunity ruling - PBS

Schumer introduces ‘No Kings Act’ in response to Supreme Court’s presidential immunity ruling PBS

Founding-Era History Doesn’t Support Trump’s Immunity Claim - Brennan Center for Justice

Founding-Era History Doesn’t Support Trump’s Immunity Claim Brennan Center for Justice

JAKs and STATs in Immunity, Immunodeficiency, and Cancer - The New England Journal of Medicine

JAKs and STATs in Immunity, Immunodeficiency, and Cancer The New England Journal of Medicine

Episode #67 - Understanding immunity - World Health Organization (WHO)

Episode #67 - Understanding immunity World Health Organization (WHO)

The scientific truth about herd immunity - University of Nebraska Medical Center

The scientific truth about herd immunity University of Nebraska Medical Center

When It Comes to Immunity, You Are What You Eat - Harvard Medical School

When It Comes to Immunity, You Are What You Eat Harvard Medical School

Court ruling imperils immunity for physicians in public service - American Medical Association

Court ruling imperils immunity for physicians in public service American Medical Association

What is community immunity? - NIH MedlinePlus Magazine (.gov)

What is community immunity? NIH MedlinePlus Magazine (.gov)

Four Ways to Keep Your Immunity Strong - My HealtheVet (.gov)

Four Ways to Keep Your Immunity Strong My HealtheVet (.gov)

Ex-Chief of Staff Mark Meadows granted immunity, tells special counsel he warned Trump about 2020 claims: Sources - ABC News - Breaking News, Latest News and Videos

Ex-Chief of Staff Mark Meadows granted immunity, tells special counsel he warned Trump about 2020 claims: Sources ABC News - Breaking News, Latest News and Videos

The effector-triggered immunity landscape of tomato against Pseudomonas syringae - Nature

The effector-triggered immunity landscape of tomato against Pseudomonas syringae Nature

Mechanism of adaptive immunity found in the fruitfly - Nature

Mechanism of adaptive immunity found in the fruitfly Nature

What should I eat to boost my immunity? - British Heart Foundation

What should I eat to boost my immunity? British Heart Foundation

Past COVID-19 infection provides some immunity but people may still carry and transmit virus - GOV.UK

Past COVID-19 infection provides some immunity but people may still carry and transmit virus GOV.UK

Judicial Immunity - United Nations Office on Drugs and Crime

Judicial Immunity United Nations Office on Drugs and Crime

Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system - Nature

Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system Nature

The quantal theory of immunity - Nature

The quantal theory of immunity Nature

New vaccine marketing campaign urges millions to boost their immunity this winter - GOV.UK

New vaccine marketing campaign urges millions to boost their immunity this winter GOV.UK

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