The IMPORTANT project aims to conduct a pragmatic clinical study with a decentralized approach for older patients with refractory advanced HR+/HER2-negative breast cancer, focusing on achieving a high level of evidence (level I) and introducing innovative approaches.
The first major innovation is personalized shared decision-making, which tailors the initial dose of CDK 4/6-inhibitors based on each patient's frailty status. This approach combines CDK 4/6-inhibitors and endocrine therapy as an initial treatment strategy, supported by clinical guidelines. Additionally, it implements a mandatory comprehensive geriatric assessment (CGA) and collects patient-reported outcome measures (PROMs) related to quality of life (QoL), potentially leading to the development of a combined geriatric QoL assessment tool.
The second innovation focuses on optimizing clinical trial recruitment by facilitating older patients and less tech-savvy individuals to participate in digital healthcare ecosystems. Multidisciplinary collaboration with experts in psychology, user interface/experience (UI/UX) design, and data collection aims to address challenges leading to underrepresentation in clinical studies.
The third innovation aims to reduce healthcare costs by developing a financial model to optimize resource utilization. This model addresses the financial burden on healthcare systems, financial toxicity for older patients, and side-effect toxicity. Health Technology Assessment processes will identify correlations to create a valuable financial model for researchers, clinicians, regulators, and policymakers.
The fourth critical innovation is the creation of a Geriatric cancer registry. This outcome will contribute to the development of a specialized registry focused on the needs of geriatric patients, not limited to cancer, and advance the state of the art in this field.
Company Details
- Address
- Örebro , Se
- Industry
- Medical Practices
- NAICS
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Ambulatory Health Care ServicesOffices of Other Health PractitionersOutpatient Care CentersOther Ambulatory Health Care ServicesOffices of All Other Health PractitionersOutpatient Mental Health and Substance Abuse CentersAll Other Ambulatory Health Care ServicesOffices of PodiatristsBlood and Organ BanksAll Other Miscellaneous Ambulatory Health Care Services
- HQ
- Örebro
- Competitors
- HeCOG-Hellenic Cooperative Oncology Group, HLRäddning: HLR utbildningar av ambulans, Viklinik, Circular Economy Foundation, Regionalt Donationscentrum, Access Heritage, Center for Education and Lifelong Learning AUTh, Sahlgrenska Universitetssjukhusets läkargrupp för innovation och teknik, Sagittarius EU Project, Australian Citizen Science Association.
Important Eu Project Questions
Important Eu Project's LinkedIn profile is https://se.linkedin.com/company/important-eu-project
Important Eu Project's industry is
Medical Practices
Important Eu Project's top competitors are
Hecog-Hellenic Cooperative Oncology Group,
Hlräddning: Hlr Utbildningar Av Ambulans,
Viklinik,
Circular Economy Foundation,
Regionalt Donationscentrum,
Access Heritage,
Center For Education And Lifelong Learning Auth,
Sahlgrenska Universitetssjukhusets Läkargrupp För Innovation Och Teknik,
Sagittarius Eu Project,
Australian Citizen Science Association.
Important Eu Project's categories are Medical Practices
