Insitro

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insitro is a data-driven drug discovery and development company that leverages machine learning and high-throughput biology to transform the way medicines are created to help patients. At insitro, we are rethinking the entire drug discovery process, from the perspective of machine learning, human genetics, and high-throughput, quantitative biology. Over the past five decades, we have seen the development of new medicines becoming increasingly more difficult and expensive, leaving many patients with significant unmet need. We’re embarking on a new approach to drug development – one that leverages machine learning and unique in vitro strategies for modeling disease state and designing new therapeutic interventions. We aim to eliminate key bottlenecks in traditional drug discovery, so we can help more people sooner and at a much lower cost to the patient and the healthcare industry. We believe that by harnessing the power of technology to interrogate and measure human biology, we can have a major impact on many diseases. We invest heavily in cutting edge bioengineering technologies to enable the construction of large-scale, high-quality data sets that are designed specifically to drive machine learning methods. Our first application is to use human genetics, functional genomics, and machine learning to build a new generation of in vitro human cell-derived disease models whose response to perturbation is designed to be predictive of human clinical outcomes. This cannot be done without great people. We are bringing together an outstanding team of people whose expertise spans multiple disciplines - life sciences, machine learning, human genetics, engineering, and drug discovery - and building a unique culture where people from diverse backgrounds work as a single team towards a common goal. We offer opportunities to collaborative people with expertise in life science and computational science. Join us to help bring better health to more people, faster and cheaper.

Company Details

Employees
278
Founded
-
Address
259 E Grand Ave, South San Francisco,california 94080,united States
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
HQ
South San Francisco, California
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News

insitro Extends Research Collaboration with Bristol Myers Squibb Leveraging insitro’s ChemML Discovery Platform - Business Wire

insitro Extends Research Collaboration with Bristol Myers Squibb Leveraging insitro’s ChemML Discovery Platform Business Wire

insitro Partners with Lilly to Innovate Small Molecule Drug Discovery Using Machine Learning - SynBioBeta

insitro Partners with Lilly to Innovate Small Molecule Drug Discovery Using Machine Learning SynBioBeta

Daphne Koller: How Insitro is Reprogramming Drug Discovery - Klover.ai

Daphne Koller: How Insitro is Reprogramming Drug Discovery Klover.ai

insitro Partners with Lilly to Build First-in-Kind Machine Learning Models to Advance Small Molecule Drug Discovery - Business Wire

insitro Partners with Lilly to Build First-in-Kind Machine Learning Models to Advance Small Molecule Drug Discovery Business Wire

Compositional Deep Probabilistic Models of DNA-Encoded Libraries - ACS Publications

Compositional Deep Probabilistic Models of DNA-Encoded Libraries ACS Publications

Insitro Cuts 22% of Workforce, Extending Runway Into 2027 - BioSpace

Insitro Cuts 22% of Workforce, Extending Runway Into 2027 BioSpace

Insitro raises $400M for machine learning-powered drug discovery efforts - Fierce Biotech

Insitro raises $400M for machine learning-powered drug discovery efforts Fierce Biotech

Daphne Koller Wants to Fix Drug Discovery With A.I.—and Real Data - observer.com

Daphne Koller Wants to Fix Drug Discovery With A.I.—and Real Data observer.com

insitro Receives $25 Million in Milestone Payments from Bristol Myers Squibb for the Achievement of Discovery Milestones and the Selection of First Novel Genetic Target for ALS - Business Wire

insitro Receives $25 Million in Milestone Payments from Bristol Myers Squibb for the Achievement of Discovery Milestones and the Selection of First Novel Genetic Target for ALS Business Wire

STATUS List | Daphne Koller - statnews.com

STATUS List | Daphne Koller statnews.com

What’s next for data driven medicine - and what AI-powered innovation needs now: Insitro CEO Daphne Koller - The World Economic Forum

What’s next for data driven medicine - and what AI-powered innovation needs now: Insitro CEO Daphne Koller The World Economic Forum

Combining AI and biology could solve drug discovery’s biggest problems - Fast Company

Combining AI and biology could solve drug discovery’s biggest problems Fast Company

insitro and UK’s INSIGHT at Moorfields Eye Hospital Announce Collaboration to Expand Research Efforts in Neurodegeneration and Related Conditions - Business Wire

insitro and UK’s INSIGHT at Moorfields Eye Hospital Announce Collaboration to Expand Research Efforts in Neurodegeneration and Related Conditions Business Wire

DEL-Dock: Molecular Docking-Enabled Modeling of DNA-Encoded Libraries - ACS Publications

DEL-Dock: Molecular Docking-Enabled Modeling of DNA-Encoded Libraries ACS Publications

Insitro, an AI biotech founded by Daphne Koller, lays off staff - statnews.com

Insitro, an AI biotech founded by Daphne Koller, lays off staff statnews.com

insitro and Lilly Enter Strategic Agreements to Advance Novel Treatments for Metabolic Diseases - Business Wire

insitro and Lilly Enter Strategic Agreements to Advance Novel Treatments for Metabolic Diseases Business Wire

insitro Hires AI and Machine Learning Visionary, Emily Fox, Ph.D., as Senior Vice President of AI/ML - Business Wire

insitro Hires AI and Machine Learning Visionary, Emily Fox, Ph.D., as Senior Vice President of AI/ML Business Wire

insitro Announces Formation of Scientific Advisory Board to Support Platform and Pipeline Advancement - Business Wire

insitro Announces Formation of Scientific Advisory Board to Support Platform and Pipeline Advancement Business Wire

insitro Hires Chief Medical Officer to Advance Therapeutic Programs Toward the Clinic - Business Wire

insitro Hires Chief Medical Officer to Advance Therapeutic Programs Toward the Clinic Business Wire

insitro Strengthens Machine Learning-Based Drug Discovery Capabilities with Acquisition of Haystack Sciences - Business Wire

insitro Strengthens Machine Learning-Based Drug Discovery Capabilities with Acquisition of Haystack Sciences Business Wire

insitro Announces $143 Million Raised in Series B Financing - Business Wire

insitro Announces $143 Million Raised in Series B Financing Business Wire

insitro Announces Five-Year Discovery Collaboration with Bristol Myers Squibb to Discover and Develop Novel Treatments for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia - Business Wire

insitro Announces Five-Year Discovery Collaboration with Bristol Myers Squibb to Discover and Develop Novel Treatments for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Business Wire

insitro Raises $400 Million in Series C Financing - Business Wire

insitro Raises $400 Million in Series C Financing Business Wire

Eli Lilly, Insitro ink a new kind of AI drug development deal - statnews.com

Eli Lilly, Insitro ink a new kind of AI drug development deal statnews.com

AI drug developer Insitro joins growing list of Bay Area biotechs to do layoffs - The Business Journals

AI drug developer Insitro joins growing list of Bay Area biotechs to do layoffs The Business Journals

Exclusive: Bristol Myers, insitro extend research deal to find a drug for new ALS target - Endpoints News

Exclusive: Bristol Myers, insitro extend research deal to find a drug for new ALS target Endpoints News

Lilly partners with AI specialist Insitro to develop metabolic medicines - BioPharma Dive

Lilly partners with AI specialist Insitro to develop metabolic medicines BioPharma Dive

Lilly and insitro team up to develop AI-powered siRNA metabolic drugs - Pharmaceutical Technology

Lilly and insitro team up to develop AI-powered siRNA metabolic drugs Pharmaceutical Technology

Machine learning enabled prediction of digital biomarkers from whole slide histopathology images - medRxiv

Machine learning enabled prediction of digital biomarkers from whole slide histopathology images medRxiv

Insitro, biotech AI’s quiet unicorn, unveils efforts in ALS, liver disease, and cancer at JPM - statnews.com

Insitro, biotech AI’s quiet unicorn, unveils efforts in ALS, liver disease, and cancer at JPM statnews.com

Insitro and Genomics England announce partnership to provide… - genomicsengland.co.uk

Insitro and Genomics England announce partnership to provide… genomicsengland.co.uk

Moorfields Eye Hospital INSIGHT research hub will collaborate with artificial intelligence development company Insitro - Ophthalmology Times Europe

Moorfields Eye Hospital INSIGHT research hub will collaborate with artificial intelligence development company Insitro Ophthalmology Times Europe

Investing in insitro - Andreessen Horowitz

Investing in insitro Andreessen Horowitz

insitro to Present at the 42nd Annual J.P. Morgan Healthcare Conference | User | poteaudailynews.com - FinancialContent

insitro to Present at the 42nd Annual J.P. Morgan Healthcare Conference | User | poteaudailynews.com FinancialContent

Lilly, Insitro Ink Unique AI Deal, Eye Novel Treatments for Metabolic Diseases - BioSpace

Lilly, Insitro Ink Unique AI Deal, Eye Novel Treatments for Metabolic Diseases BioSpace

Insitro raises $143m Series B - drugdiscoverytrends.com

Insitro raises $143m Series B drugdiscoverytrends.com

Merck’s Roger Perlmutter joins board of AI drug discovery startup Insitro - statnews.com

Merck’s Roger Perlmutter joins board of AI drug discovery startup Insitro statnews.com

Insitro boosts executive team with Aimmune development chief and Pfizer vet - Fierce Biotech

Insitro boosts executive team with Aimmune development chief and Pfizer vet Fierce Biotech

Stealthy Insitro opens up—starting with Gilead deal worth up to $1.05B - Fierce Biotech

Stealthy Insitro opens up—starting with Gilead deal worth up to $1.05B Fierce Biotech

Insitro, Backed by Jeff Bezos, Signs Gilead Deal to Make NASH Drugs - businessinsider.com

Insitro, Backed by Jeff Bezos, Signs Gilead Deal to Make NASH Drugs businessinsider.com

insitro Bolsters Machine-Learning Platform with Haystack Sciences Acquisition - BioSpace

insitro Bolsters Machine-Learning Platform with Haystack Sciences Acquisition BioSpace

Top 25 AI Companies Leading Innovation in 2025 - Analytics Insight

Top 25 AI Companies Leading Innovation in 2025 Analytics Insight

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