Jandus Lab

Defense is a key strategy in many domains: in the jungle, in sport, in war, but also in the human body. In humans a dedicated system, called the immune system, is able to specifically discriminate between potentially harmful and harmless agents, and react accordingly. Increasing evidence shows that cancer cells, despite belonging to the human body, can be recognized and successfully eliminated if our immune system has been optimally trained. Yet, as exemplified by the increasing number of cancer patients worldwide, elimination of tumors is often unsuccessful, due to numerous strategies employed by cancer cells to impair immune cell function. Our research focuses on elucidating the characteristics and function of cytokine secreting immune cell populations in cancer patients. We are using a combination of complementary high-throughput innovative technologies to analyse patient samples and define individual cells in the tumor microenvironment. This strategy will allow us to identify potential therapeutic targets, with the eventual aim of restoring immune function and clearing cancer cells. This novel treatment strategy, immunotherapy, is adhering to the proverb which says, the best defense is a good offense. This page is maintained by members of the Jandus Lab to share our research updates, events, and lab activities. The content reflects the collaborative efforts of the research team.