Larkspur Biosciences

Larkspur Biosciences company information, Employees & Contact Information

Targeting enzymes that control cancer cell state and fitness make cancer cells susceptible to intrinsic and immune-mediated killing but drugging these pathways has been limited by poor tractability. Larkspur develops small molecules that overcome these limitations, decreasing cancer cell fitness and sensitizing them to intrinsic and immune-driven mechanisms of killing. LarkX, our proprietary machine-learning-enabled gene signature platform, identifies pathways with cancer cell-intrinsic adaptations that drive immune evasion. This identifies novel targets that mediate pathological cell-to-cell communication. Larkspur’s clinical development focuses on biomarker-driven cancer patient cohorts to achieve early proof-of-concept. Our first-in-class pipeline programs are initially focused on colorectal cancer (CRC), with opportunities to expand to multiple cancers. We believe that transformational discoveries are found at the interface between disciplines. With a proven track record of drug discovery and development, our team is passionate about solving hard problems and driven to deliver new medicines to cancer patients with significant unmet needs. At Larkspur, we grow together, building a culture that highly values joy, trust, and courage.

Company Details

Employees
17
Founded
-
Address
One Canal Park,
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
HQ
Cambridge, MA
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News

Needham Times Events - 8th Annual TPD & Induced Proximity Summit - Wicked Local

Needham Times Events - 8th Annual TPD & Induced Proximity Summit Wicked Local

Slim Man: Rat Pack Duo at Larkspur! - Hi Desert Star

Slim Man: Rat Pack Duo at Larkspur! Hi Desert Star

Larkspur Biosciences Announces Discovery of LRK-4189, a First-in-Class Degrader of the Lipid Kinase PIP4K2C, for the Treatment of Microsatellite Stable (MSS) Colorectal Cancer at the ACS Fall 2025 Meeting - GlobeNewswire

Larkspur Biosciences Announces Discovery of LRK-4189, a First-in-Class Degrader of the Lipid Kinase PIP4K2C, for the Treatment of Microsatellite Stable (MSS) Colorectal Cancer at the ACS Fall 2025 Meeting GlobeNewswire

Larkspur council upholds fines over tree removals - Marin Independent Journal

Larkspur council upholds fines over tree removals Marin Independent Journal

Northbound I-25 reopened after multi-vehicle crash in Larkspur - KUSA.com

Northbound I-25 reopened after multi-vehicle crash in Larkspur KUSA.com

Larkspur is a Real Charmer in the Garden—Here's How to Grow It - Better Homes & Gardens

Larkspur is a Real Charmer in the Garden—Here's How to Grow It Better Homes & Gardens

Noetik Names Dr. Emily Corse Executive Vice President of Therapeutics to Accelerate AI-Powered Therapeutics Pipeline - BioSpace

Noetik Names Dr. Emily Corse Executive Vice President of Therapeutics to Accelerate AI-Powered Therapeutics Pipeline BioSpace

Larkspur-Corte Madera School District trustee resigns - Marin Independent Journal

Larkspur-Corte Madera School District trustee resigns Marin Independent Journal

Plane crashed near Larkspur during lesson on emergency procedures - The Denver Post

Plane crashed near Larkspur during lesson on emergency procedures The Denver Post

Larkspur Biosciences Launches with $35.5 Million in - GlobeNewswire

Larkspur Biosciences Launches with $35.5 Million in GlobeNewswire

Larkspur adopts state green building codes - Marin Independent Journal

Larkspur adopts state green building codes Marin Independent Journal

Marin agency forges ahead with major housing plan in Larkspur - Marin Independent Journal

Marin agency forges ahead with major housing plan in Larkspur Marin Independent Journal

Larkspur to abandon rental registry - Marin Independent Journal

Larkspur to abandon rental registry Marin Independent Journal

SMART expands Larkspur shuttle service for ferry riders - Marin Independent Journal

SMART expands Larkspur shuttle service for ferry riders Marin Independent Journal

Larkspur council considers outdoor space for new library - Marin Independent Journal

Larkspur council considers outdoor space for new library Marin Independent Journal

Larkspur postpones vote on off-leash dogs at Piper Park - Marin Independent Journal

Larkspur postpones vote on off-leash dogs at Piper Park Marin Independent Journal

Larkspur to pull out of rental housing authority - Marin Independent Journal

Larkspur to pull out of rental housing authority Marin Independent Journal

Restaurant review: Tavola Rustica a smash hit in Larkspur - Marin Independent Journal

Restaurant review: Tavola Rustica a smash hit in Larkspur Marin Independent Journal

Larkspur council ‘alarmed’ by housing partner’s finances - Marin Independent Journal

Larkspur council ‘alarmed’ by housing partner’s finances Marin Independent Journal

Larkspur Biosciences to Present New Mechanistic Data on the Role of Pin1 in Modulating the Fibroblast – Cancer Axis at SITC 2023 - Yahoo Finance

Larkspur Biosciences to Present New Mechanistic Data on the Role of Pin1 in Modulating the Fibroblast – Cancer Axis at SITC 2023 Yahoo Finance

Meeting Today For Proposed New Larkspur Library - San Francisco YIMBY

Meeting Today For Proposed New Larkspur Library San Francisco YIMBY

This Town Is Suddenly the Coolest Place in Marin County - The San Francisco Standard

This Town Is Suddenly the Coolest Place in Marin County The San Francisco Standard

Larkspur Poisoning of Cattle: Plant and Animal Factors that Influence Plant Toxicity - BioOne Complete

Larkspur Poisoning of Cattle: Plant and Animal Factors that Influence Plant Toxicity BioOne Complete

Larkspur neighborhood to consider $22 million bond for lagoon repairs - Marin Independent Journal

Larkspur neighborhood to consider $22 million bond for lagoon repairs Marin Independent Journal

Larkspur: Stately Back-Row Plant for the Perennial Border - The Spruce

Larkspur: Stately Back-Row Plant for the Perennial Border The Spruce

Why Larkspur is dangerous for cattle and how to manage it - Farm Talk

Why Larkspur is dangerous for cattle and how to manage it Farm Talk

Former Novartis executive director heads up new immuno-oncology play - The Business Journals

Former Novartis executive director heads up new immuno-oncology play The Business Journals

Camping near Castle Rock, Larkspur and Monument, Colorado - Uncover Colorado

Camping near Castle Rock, Larkspur and Monument, Colorado Uncover Colorado

NewPoint Provides $22.5M in Financing for The Larkspur Workforce Housing Development in Victor, Idaho - REBusinessOnline

NewPoint Provides $22.5M in Financing for The Larkspur Workforce Housing Development in Victor, Idaho REBusinessOnline

Is it a Mountain Bike or a City Bike? The Marin Larkspur 2 is Both! - Bikerumor

Is it a Mountain Bike or a City Bike? The Marin Larkspur 2 is Both! Bikerumor

Global Coalition for Adaptive Research, Biohaven, and Vigeo Announce Commencement of Biohaven’s Troriluzole and Vigeo’S VT1021 in GBM AGILE Trial - Business Wire

Global Coalition for Adaptive Research, Biohaven, and Vigeo Announce Commencement of Biohaven’s Troriluzole and Vigeo’S VT1021 in GBM AGILE Trial Business Wire

Sarah Garlington Obituary (2014) - Larkspur, CA - San Francisco Chronicle - Legacy obituary

Sarah Garlington Obituary (2014) - Larkspur, CA - San Francisco Chronicle Legacy obituary

New Janis Joplin bio captures singer’s tragic life, happiness she found in Marin - The Mercury News

New Janis Joplin bio captures singer’s tragic life, happiness she found in Marin The Mercury News

Co-Masonic history still alive in present-day Larkspur - The Denver Post

Co-Masonic history still alive in present-day Larkspur The Denver Post

Marin bicyclists get San Rafael-Larkspur tunnel - SFGATE

Marin bicyclists get San Rafael-Larkspur tunnel SFGATE

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