LC Sciences

LC Sciences is a global biotechnology company providing products and services to genomics and proteomics researchers across an array of markets for nucleic acid/protein analysis, biomarker-discovery and drug development. Our innovative products and comprehensive services are based on several unique, core technology platforms developed by the scientists here at LC Sciences. A wide range of microarray service products are based on our µParaflo® microfluidic on-chip synthesis technology. This technology enables us to provide unique and customizable arrays of oligonucleotides, peptides, and their analog molecules. Our line of microarray services includes microRNA profiling, custom oligonucleotide (aptamer) screening, and peptide arrays for epitope mapping, protein kinase substrate profiling, and phosphopeptide binding assays. The OligoMix® technology has significantly reduced the cost and increased the speed of highly multiplexing genome-scale experiments such as exploration of small RNAs and designer gene/DNA library synthesis. OligoMix® technology has been applied to library construction of various biomolecules, sequence capture for targeted next-gen sequencing, and synthetic biology. The recently developed OligoFix™ strategy for error correction of microarray synthesized oligos has greatly improved the utility of OligoMix® for synthetic biology applications. The game-changing VariantPro™ multiplex-PCR based targeted sequencing system provides a simple, robust process delivering cost savings due to improved sequencing efficiency. Unlike singleplex methods with limited scalability and inflexible or traditional multiplex methods that suffer from primer induced variation in coverage requiring additional sequencing depth, VariantPro™ combines the specificity of a singleplex PCR reaction with the scalability of a multiplex reaction into a single step via relay-PCR, requiring less sequencing depth per sample.