Mrc Holland

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MRC Holland is a biotechnology company well-known for its SALSA® MLPA® technology, the gold standard in the detection of gene copy number variation and epigenetics. MLPA assays are used worldwide to study hereditary disorders and tumours. In addition, MRC Holland also offers SALSA® digitalMLPA™, a technology offering unparalleled CNV detection in NGS, and a SALSA® Melt Assay for SMA newborn screening. The company’s mission to bring high quality CNV detection within reach for all relevant disorders has led to the development of over 300 different assays, all hallmarked by their ease-of-use and clear results.

Company Details

Employees
104
Founded
-
Address
Willem Schoutenstraat 1, Amsterdam,1057dl,netherlands
Phone
+31 88 865 7200
Email
in****@****and.com
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
Website
mlpa.com
Keywords
Engineer jobs.
HQ
Amsterdam
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News

Diagnostic yield of expanded carrier screening of a multi-ethnic population in yunnan, China - Nature

Diagnostic yield of expanded carrier screening of a multi-ethnic population in yunnan, China Nature

Screening of 22q11.2DS Using Multiplex Ligation-Dependent Probe Amplification as an Alternative Diagnostic Method - Wiley Online Library

Screening of 22q11.2DS Using Multiplex Ligation-Dependent Probe Amplification as an Alternative Diagnostic Method Wiley Online Library

MLPA-Based Analysis of Copy Number Variation in Plant Populations - Frontiers

MLPA-Based Analysis of Copy Number Variation in Plant Populations Frontiers

MLPA: Tapping Into The U.S. Natural Gas Boom With A Cheap ETF - Seeking Alpha

MLPA: Tapping Into The U.S. Natural Gas Boom With A Cheap ETF Seeking Alpha

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study - Nature

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study Nature

Three Variants Affecting Exon 1 of Ectodysplasin A Cause X-Linked Hypohidrotic Ectodermal Dysplasia: Clinical and Molecular Characteristics - Frontiers

Three Variants Affecting Exon 1 of Ectodysplasin A Cause X-Linked Hypohidrotic Ectodermal Dysplasia: Clinical and Molecular Characteristics Frontiers

MLPA: Momentum Weaker, But Value And Income Remain - Seeking Alpha

MLPA: Momentum Weaker, But Value And Income Remain Seeking Alpha

Establishment and application of a novel method based on single nucleotide polymorphism analysis for detecting β-globin gene cluster deletions - Nature

Establishment and application of a novel method based on single nucleotide polymorphism analysis for detecting β-globin gene cluster deletions Nature

Cytoplasmic MSH2 Related to Genomic Deletions in the MSH2/EPCAM Genes in Colorectal Cancer Patients With Suspected Lynch Syndrome - Frontiers

Cytoplasmic MSH2 Related to Genomic Deletions in the MSH2/EPCAM Genes in Colorectal Cancer Patients With Suspected Lynch Syndrome Frontiers

Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy - Nature

Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy Nature

Theragnosis for Duchenne Muscular Dystrophy - Frontiers

Theragnosis for Duchenne Muscular Dystrophy Frontiers

HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study - Nature

HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study Nature

Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel - Nature

Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel Nature

Metabolomics reveals novel blood plasma biomarkers associated to the BRCA1-mutated phenotype of human breast cancer - Nature

Metabolomics reveals novel blood plasma biomarkers associated to the BRCA1-mutated phenotype of human breast cancer Nature

MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas - Nature

MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas Nature

Early-onset seizures due to mosaic exonic deletions of CDKL5 in a male and two females - Nature

Early-onset seizures due to mosaic exonic deletions of CDKL5 in a male and two females Nature

Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region - Nature

Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region Nature

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers - Nature

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers Nature

Novel deletion of the E3A ubiquitin protein ligase gene detected by multiplex ligation-dependent probe amplification in a patient with Angelman syndrome | Experimental & Molecular Medicine - Nature

Novel deletion of the E3A ubiquitin protein ligase gene detected by multiplex ligation-dependent probe amplification in a patient with Angelman syndrome | Experimental & Molecular Medicine Nature

Deletions, not duplications or small mutations, are the predominante new mutations in the dystrophin gene - Nature

Deletions, not duplications or small mutations, are the predominante new mutations in the dystrophin gene Nature

Complete COL1A1 allele deletions in osteogenesis imperfecta - Nature

Complete COL1A1 allele deletions in osteogenesis imperfecta Nature

Spinal Muscular Atrophy in the Black South African Population: A Matter of Rearrangement? - Frontiers

Spinal Muscular Atrophy in the Black South African Population: A Matter of Rearrangement? Frontiers

MLPA: Pipeline Income For The Yield Hungry Energy Investor - Seeking Alpha

MLPA: Pipeline Income For The Yield Hungry Energy Investor Seeking Alpha

Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma - Nature

Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma Nature

Deletion and duplication screening in the DMD gene using MLPA - Nature

Deletion and duplication screening in the DMD gene using MLPA Nature

Nail–Patella Syndrome: clinical and molecular data in 55 families raising the hypothesis of a genetic heterogeneity - Nature

Nail–Patella Syndrome: clinical and molecular data in 55 families raising the hypothesis of a genetic heterogeneity Nature

Demographic characteristics, clinical and laboratory features, and the distribution of pathogenic variants in the CFTR gene in the Cypriot cystic fibrosis (CF) population demonstrate the utility of a national CF patient registry - Orphanet Journal of Rare Diseases

Demographic characteristics, clinical and laboratory features, and the distribution of pathogenic variants in the CFTR gene in the Cypriot cystic fibrosis (CF) population demonstrate the utility of a national CF patient registry Orphanet Journal of Rare Diseases

Identification of entire LMX1B gene deletions in nail patella syndrome: evidence for haploinsufficiency as the main pathogenic mechanism underlying dominant inheritance in man - Nature

Identification of entire LMX1B gene deletions in nail patella syndrome: evidence for haploinsufficiency as the main pathogenic mechanism underlying dominant inheritance in man Nature

Genomic Diagnosis for Pediatric Disorders: Revolution and Evolution - Frontiers

Genomic Diagnosis for Pediatric Disorders: Revolution and Evolution Frontiers

AMLP and MLPA: Which MLP ETF Is Right for Your Portfolio? - ETF Trends

AMLP and MLPA: Which MLP ETF Is Right for Your Portfolio? ETF Trends

Comparing the 2 Largest MLP ETFs: AMLP and MLPA - ETF Trends

Comparing the 2 Largest MLP ETFs: AMLP and MLPA ETF Trends

The clinical spectrum of complete FBN1 allele deletions - Nature

The clinical spectrum of complete FBN1 allele deletions Nature

SHOX Duplication and Tall Stature in a Patient with Xq Deletion and Vascular Disease - Wiley Online Library

SHOX Duplication and Tall Stature in a Patient with Xq Deletion and Vascular Disease Wiley Online Library

MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB - BMC Cancer

MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB BMC Cancer

Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution - Nature

Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution Nature

Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1 - Nature

Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1 Nature

The unfolding clinical spectrum of holoprosencephaly due to mutations in SHH, ZIC2, SIX3 and TGIF genes - Nature

The unfolding clinical spectrum of holoprosencephaly due to mutations in SHH, ZIC2, SIX3 and TGIF genes Nature

A new diagnostic workflow for patients with mental retardation and/or multiple congenital abnormalities: test arrays first - Nature

A new diagnostic workflow for patients with mental retardation and/or multiple congenital abnormalities: test arrays first Nature

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