MuSigmas Consultants S.L.

MuSigmas (formerly Mukherjee-Consultants) provides statistical planning support for early and late phase clinical trials and observational studies. We specialize in Adaptive Designs including Bayesian Designs and in applying machine learning for biomarker discoveries and diagnostic device development. Apart from design and analysis services, we also provide support for regulatory defence of clinical trial designs and protocols and Data Monitoring Committee (DMC) related services. While we cover all therapeutic areas, we have extensive experience in Oncology, CVD, CNS, Rare diseases, Vaccine trials and Medical devices. We are also actively involved in developing cutting-edge statistical tools and software to empower statisticians, data scientists and clinicians. Our expertises: • Adaptive Designs • Bayesian Statistics and Bayesian Designs • Regulatory Defence of Protocols and Study Designs • Master Protocol Study Designs • Simulation Guided Designs • Diagnostics Development and Validation • Design of Vaccine Trials • Strategies for Real World Evidence (RWE) and Post-marketing studies • Data Safety Monitoring Committee (DMC/DSMB) Services • Statistical Programming using R/Python • Training in Adaptive Designs and Bayesian Statistics • Machine Learning (ML) Applications for Biomarker Discoveries and Diagnostics • R/Python package validation capabilities