Mutation Analysis Facility (MAF)

The purpose and mission of the Mutation Analysis Core Facility (MAF) is to help scientists at Karolinska Institutet, its associated hospitals, and other academic institutions to perform genetic, epigenetic and genetic-epidemiological research in order to identify and assess genetic factors involved in different disease processes. Single nucleotide polymorphism (SNP) genotyping has been offered since 2003 and from 2010 we also perform targeted epigenetic analyses with the Agena MALDI-TOF technique. We also carry out genome wide analysis using the Illumina iScan platform. There is a broad portfolio of Beadchips for the system which encompasses: genotyping, CNV analysis, and DNA methylation. MAF has an accreditation of its organization, facilities and the Agena genotyping and DNA methylation analysis methods according to ISO/IEC 17025 by SWEDAC.