Onena Medicines is a biopharmaceutical company with a pipeline of first-in-class antibody medicines to treat recurrent and metastatic cancers and selected rare diseases. Onena’s drugs neutralize a new class of secreted ancient growth factors, conserved across species, called Dual SMAD Inhibiting Proteins (DSIPs), that program cancer cells to grow and resist chemotherapy. Blocking DSIPs, as demonstrated in-vivo by Onena, simultaneously reactivates physiological TGF-β and BMP signaling and elicits cellular reprogramming, resulting in cancer cells accepting environmental cell death signals from BMPs and Activins. Onena has developed a proprietary AI-centric antibody drug discovery platform that rapidly generates anti-DSIP neutralizing antibodies, even when no crystal structure of the antigen is available. OMED-101, Onena’s anti-LEFTY1/2 lead candidate antibody, has demonstrated broad efficacy against breast, colorectal and brain cancers without observable toxicities in preclinical models. Through its unique platform, Onena Medicines has discovered several DSIPs and aims to advance multiple neutralizing DSIP antibody drugs into clinical development in the next three years.
Company Details
- Employees
- 12
- Founded
- -
- Address
- Gewerbestrasse 24, Switzerland Innovation Park Basel Area Ag,switzerland
- Industry
- Biotechnology
- Website
- onenameds.com
- Keywords
- Oncology, Antibody engineering, Rare diseases, Biotechnology, Biologics, Drug discovery, Drug development, Assay, Cancer, Patient, Clinical, Clinical Trial, Switzerland, Spain, Basel.
- HQ
- Basel, Switzerland
Onena Medicines Questions
Onena Medicines's website is onenameds.com
Onena Medicines's LinkedIn profile is https://ch.linkedin.com/company/onenameds
Onena Medicines has
12 employees.
View email and phone details for 12
employees at Onena Medicines.
Onena Medicines's industry is
Biotechnology
Onena Medicines's top competitors are
Cellestia Biotech,
Miramoon Pharma,
Anaveon Ag,
Captor Therapeutics Sa,
Bioversys Ag,
Ulma Medical Technologies,
Deneb Medical,
Memo Therapeutics Ag,
Vivebiotech,
Biocopy Ag.
Onena Medicines's categories are Biotechnology
Onena Medicines's founding year is 2019
