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TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration PNAS

An Overview of MicroRNAs as Biomarkers of ALS Frontiers

CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro Nature

Helping You Understand ALS The ALS Association

Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling Journal of Neuroscience

Understanding the different types of ALS Neurology® Journals

Therapeutic targeting of ALS pathways: Refocusing an incomplete picture Wiley Online Library

Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2 ScienceDirect.com

The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS Frontiers

Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology Nature

New Report Highlights Progress Made Because of ALS Ice Bucket Challenge The ALS Association

Natural history of ALS Neurology® Journals

Reduced levels of ALS gene DCTN1 induce motor defects in Drosophila Frontiers

An EEG & eye-tracking dataset of ALS patients & healthy people during eye-tracking-based spelling system usage Nature

Retinal fingerprints of ALS in patients: Ganglion cell apoptosis and TDP-43/p62 misplacement Frontiers

Molecular subtypes of ALS are associated with differences in patient prognosis Nature

Essential Roles and Risks of G-Quadruplex Regulation: Recognition Targets of ALS-Linked TDP-43 and FUS Frontiers

model of ALS reveals that motor neurons express muscle-associated genes in non-disease states Frontiers

Cysteine Modifications in the Pathogenesis of ALS Frontiers

First Principles Calculation of Protein–Protein Dimer Affinities of ALS-Associated SOD1 Mutants Frontiers

In vivo genome editing improves motor function and extends survival in a mouse model of ALS Science | AAAS

The multistep hypothesis of ALS revisited Neurology® Journals

Calcium, mitochondria, and the pathogenesis of ALS: the good, the bad, and the ugly Frontiers

ASCs-Exosomes Recover Coupling Efficiency and Mitochondrial Membrane Potential in an in vitro Model of ALS Frontiers

Correlational Analysis of ALS Progression and Serum NfL Measured by Simoa Assay in Chinese Patients Frontiers

Stabilization of V1 interneuron-motor neuron connectivity ameliorates motor phenotype in a mouse model of ALS Nature

Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons Nature

Automatic detection of ALS from single-trial MEG signals during speech tasks: a pilot study Frontiers

The influence of environmental risk factors in the development of ALS in the Mediterranean Island of Cyprus Frontiers

Machine learning-based proteomics profiling of ALS identifies downregulation of RPS29 that maintains protein homeostasis and STMN2 level | Communications Biology Nature

Candida albicans Agglutinin-Like Sequence (Als) Family Vignettes: A Review of Als Protein Structure and Function Frontiers

Nuclear RNA transcript levels modulate nucleocytoplasmic distribution of ALS/FTD-associated protein FUS Nature

Cellular analysis of SOD1 protein-aggregation propensity and toxicity: a case of ALS with slow progression harboring homozygous SOD1-D92G mutation Nature

Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials Neurology® Journals

Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth PNAS

Analysis of ALS-related proteins during herpes simplex virus-2 latent infection Journal of Neuroinflammation

Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity ScienceDirect.com

Tethering-induced destabilization and ATP-binding for tandem RRM domains of ALS-causing TDP-43 and hnRNPA1 Nature

Enhanced axonal regeneration of ALS patient iPSC-derived motor neurons harboring SOD1 Nature

ATP induces folding of ALS-causing C71G-hPFN1 and nascent hSOD1 Nature

Rapid detection and specific identification of offals within minced beef samples utilising ambient mass spectrometry Nature

Predicting the future of ALS: the impact of demographic change and potential new treatments on the prevalence of ALS in the United Kingdom, 2020–2116 Taylor & Francis Online

Prematurely terminated intron-retaining mRNAs invade axons in SFPQ null-driven neurodegeneration and are a hallmark of ALS Nature

Parkin is a disease modifier in the mutant SOD1 mouse model of ALS | EMBO Molecular Medicine EMBO Press

Distinct Expression Levels of ALS, LIP, and SAP Genes in Candida tropicalis with Diverse Virulent Activities Frontiers

Delayed Diagnosis and Diagnostic Pathway of ALS Patients in Portugal: Where Can We Improve? Frontiers

Lipidomics Reveals Cerebrospinal-Fluid Signatures of ALS Nature

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS Nature

The fecal microbiome of ALS patients ScienceDirect.com

Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS Nature

Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS Nature

Effects of ALS-associated TANK binding kinase 1 mutations on protein–protein interactions and kinase activity PNAS

Tempol improves neuroinflammation and delays motor dysfunction in a mouse model (SOD1G93A) of ALS Journal of Neuroinflammation

Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1 -linked mouse models of ALS Nature

C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD ScienceDirect.com

ALS Along the Axons – Expression of Coding and Noncoding RNA Differs in Axons of ALS models Nature

Drug Combination Slows Progression Of ALS And Could Mark 'New Era' In Treatment NPR

The epidemiology of ALS: a conspiracy of genes, environment and time Nature

Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALS Journal of Biomedical Science

The Dish: That’s Judge Judy behind shades at masquerade fete Greenwich Time

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes Nature

RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously self-assembles into amyloid fibrils Nature

SOD1-positive aggregate accumulation in the CNS predicts slower disease progression and increased longevity in a mutant SOD1 mouse model of ALS Nature

The Intense Psychological Burden of ALS, the Enduring Strength of People Living With ALS, and the Tools We Can Use to Help Psychiatrist.com

T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS PNAS

Sirtuins as therapeutic targets of ALS Nature

A robust TDP-43 knock-in mouse model of ALS Acta Neuropathologica Communications

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs Nature

Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD Molecular Neurodegeneration

Greenwich singer/restaurateur to celebrate release of new album Greenwich Time

"Scandal" star a special guest at AmeriCares benefit Greenwich Time

Iron Metabolism Disturbance in a French Cohort of ALS Patients Wiley Online Library