Proteomics-based Research Initiative for Non-Cytochrome P450 Enzymes (PRINCE) is a research collaboration between Washington State University and multiple pharmaceutical companies. The overarching objective of PRINCE is to enable prediction of drug metabolism mediated by non-cytochrome P450 (non-CYP) enzymes. The research utilizes quantitative mass spectrometry proteomics for:
1) The characterization of differential tissue expression, interindividual variability, and inter-species differences in non-CYP enzymes
2) In vitro to in vivo extrapolation (IVIVE) of non-CYP metabolism for predicting drug clearance and fractional contribution of individual enzymes
3) Physiologically-based pharmacokinetic (PBPK) modeling of drugs metabolized by non-CYP enzymes
Company Details
- Address
- 202 E Spokane Falls Blvd, Spokane,washington 99202,united States
- Industry
- Technology, Information And Internet
- HQ
- Spokane, Washington
Prince: Proteomics-Based Research Initiative For Non-Cytochrome P450 Enzymes Questions
Prince: Proteomics-Based Research Initiative For Non-Cytochrome P450 Enzymes's website is https://labs.wsu.edu/prasadlab/prince-program/
Prince: Proteomics-Based Research Initiative For Non-Cytochrome P450 Enzymes's LinkedIn profile is https://www.linkedin.com/company/princeatprasadlab
Prince: Proteomics-Based Research Initiative For Non-Cytochrome P450 Enzymes's industry is
Technology, Information and Internet
Prince: Proteomics-Based Research Initiative For Non-Cytochrome P450 Enzymes's top competitors are
Wsu College Of Pharmacy And Pharmaceutical Sciences,
Iit Delhi - Abu Dhabi,
Washington State University Spokane,
Prasad Lab I Cchmc.
Prince: Proteomics-Based Research Initiative For Non-Cytochrome P450 Enzymes's categories are Technology, Information and Internet
