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Cytoplasmic PXR regulates glucose metabolism by binding mRNAs and modulating their stability Nature

The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model Nature

PXR-dependant dysregulation of glucose metabolism induced by chronic exposure to NOAEL-level pesticide cocktail in mice ScienceDirect.com

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity PNAS

Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions Frontiers

Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation ACS Publications

Effects of Dicyclohexyl Phthalate Exposure on PXR Activation and Lipid Homeostasis in Mice EHP Publishing (.gov)

An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice Nature

Molecular targets of PXR-dependent ethanol-induced hepatotoxicity in female mice ScienceDirect.com

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids PNAS

PXR triggers YAP-TEAD binding and Sirt2-driven YAP deacetylation and polyubiquitination to promote liver enlargement and regeneration in mice ScienceDirect.com

PXR as the tipping point between innate immune response, microbial infections, and drug metabolism ScienceDirect.com

Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR Nature

Discrepancy in interactions and conformational dynamics of pregnane X receptor (PXR) bound to an agonist and a novel competitive antagonist ScienceDirect.com

Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice ScienceDirect.com

Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR ScienceDirect.com

PXR: a center of transcriptional regulation in cancer ScienceDirect.com

The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids ScienceDirect.com

PXR activation impairs hepatic glucose metabolism partly via inhibiting the HNF4α–GLUT2 pathway ScienceDirect.com

Astilbin alleviates hepatic fibrosis through PXR-PINK1/Parkin pathway: A new strategy by regulating hepatic stellate cells-macrophage crosstalk ScienceDirect.com

Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches ACS Publications

Comment on “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI” Science | AAAS

B3galt5 functions as a PXR target gene and regulates obesity and insulin resistance by maintaining intestinal integrity Nature

Novel inhibitor insights offer pathway to preventing PXR-associated drug resistance St. Jude Children's Research Hospital

Attenuation of bile acid-mediated FXR and PXR activation in patients with Crohn’s disease Nature

The role of pregnane X receptor (PXR) in substance metabolism Frontiers

PXR variants: the impact on drug metabolism and therapeutic responses ScienceDirect.com

TPX2 enhances the transcription factor activation of PXR and enhances the resistance of hepatocellular carcinoma cells to antitumor drugs Nature

PXR mediates mifepristone-induced hepatomegaly in mice Nature

Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction ACS Publications

Bioinformatis analysis reveals possible molecular mechanism of PXR on regulating ulcerative colitis Nature

Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches | Journal of Medicinal Chemistry ACS Publications

Exploring the PXR ligand binding mechanism with advanced Molecular Dynamics methods | Scientific Reports Nature

Activation of PXR by alantolactone ameliorates DSS-induced experimental colitis via suppressing NF-κB signaling pathway Nature

Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel Disease Frontiers

Novel complex of HAT protein TIP60 and nuclear receptor PXR promotes cell migration and adhesion Nature

Targeting the PXR–TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis Nature

PXR interaction with p53: a meeting of two masters Nature

Association of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity Nature

Statin-activated nuclear receptor PXR promotes SGK2 dephosphorylation by scaffolding PP2C to induce hepatic gluconeogenesis Nature

Pxr, car and drug metabolism Nature

Rapala PXR Jowler 127 Review Wired2Fish

The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4 Nature

Michael Young relaunches PXR-5 watch that caused "queues blocking the corridors" Dezeen

Spinlock PXR Remote: Ash Holmes explains this great existing product modification Yachts and Yachting