RostLab - Computational Biology

The lab's research is driven by a conviction that protein and DNA sequences encode a significant core of information about the ultimate structure and function of genetic material and its gene products. Research goals of the lab involve using protein and DNA sequences along with evolutionary information to predict a protein's: overall function, interaction partners, secondary structure, disordered regions, subcellular localization, membrane spanning protein structure, intra-chain residue contacts, cell cycle control, and domain boundaries. Another significant research focus is to improve the effectiveness and efficiency of structural genomics projects' ability to determine the structures of proteins on a large scale.