SCALE-IT Project_Ethics

SCALE-IT- SCALING UP CAPACITY TO SUPPORT CONDUCT OF CLINICAL TRIALS IN THE EAST AFRICAN COMMUNITY The East African Community (EAC) has experienced significant increase in volume and complexity of clinical research driven by epidemics of emerging and remerging infectious diseases such as HIV, Ebola and COVID-19, requiring expertise in scientific and ethical review and conduct of research and a robust and pragmatic research regulatory framework. Goal: The overall goal is to strengthen scientific and ethics capacity in EAC for high quality research review, conduct and oversight, at international standards. The specific objectives are: 1. To train NRRA personnel, REC members, researchers and clinicians on scientific and ethics review and conduct of research with emerging and complex study designs including adaptive platform trials 2. To train NRRA personnel and REC members on oversight, monitoring and pharmacovigilance of clinical trials 3. To train NRRA personnel, REC and research administrators on personal effectiveness and leadership skills (PELS) to manage the increasingly complex research processes. SCALE-IT is being implemented within a partnership of Infectious Diseases Institute (IDI), Uganda, Médecins Sans Frontières (MSF) EPICENTRE ,France (EU partner), Kenya Medical Research Institute (KEMRI), Kenya and partners from the 6 EAC states, with East Africann Health Research Commission, EAHRC @EAHRC_eahealth as the nucleus for coordination and dissemination of results. Funder @EDCTP3