Signifience

Signifience is a Biostatistics consulting company with high-level expertise in clinical data analytics for Pharmaceutical companies and Biotechs We deeply believe that the success of every scientific research relies on the quality of the data and the precision of the analytical methodology applied. Our mission is to provide full statistical support to medical & pharma research teams at the core of each data exploitation phase. We are involved in clinical studies sponsored by TOP 10 Pharmaceutical companies, as well as in highest level of Academic research. Our area of expertise include : - Support in statistical aspect of study designs (Interim analysis, Sample size and power calculations) in Phases I to IV - Strong experience in RWE , Data generation for Medical Affairs and Post hoc analyses - Data analysis for clinical trials and observational studies (RCTs, Real-World data, National registries etc..) - Development of statistical sections for study protocols (study endpoints, missing values handling etc..) - Creation of Statistical Analysis Plans (SAP) - Output templates proposal (Data Presentation Plans, Mocks tables etc..) - Support of Final Study Reports - Post Hoc & Meta Analyses