SISCAPA Assay Technologies

SISCAPA technology is the smart shortcut to sensitive quantitation of protein biomarkers and targets. SISCAPA assays combine the precision of MRM mass spectrometry with the power of affinity enrichment to deliver a superior alternative to conventional immunoassays for protein quantitation. The SISCAPA workflow is highly automated and exploits familiar LC-MS/MS platforms widely used for drug and metabolite quantitation. At SAT we believe quantitation of proteins in biologic samples provides an actionable measure of the state of health, disease and treatment. We provide services and products for sequence-specific protein quantitation and robust generation of data in an automated, multiplexed and high throughput manner. Analysis is carried out using a generic workflow, allowing for validation and industrialization of processes for such applications as biomarker validation, protein bioanalysis, pathway research for therapeutic development and monitoring and for use in laboratory-developed tests. SISCAPA assays enable multiplexed quantitation of proteins over many orders of magnitude dynamic range. The generic, automated workflow ensures robust results with high throughput and precision. SISCAPA services include complete Assay Reagent Development or specialized Assay Implementation to maximize your up-time and help you quantitate proteins with unmatched precision. Our pipeline has generated reagents for SISCAPA quantitation of more than 250 different proteins to date, providing an unparalleled experience base.