SONOCRAFT

SONOCRAFT is a visionary EU-funded initiative at the forefront of cardiac tissue engineering. Its mission is to address the pressing need for reliable, physiologically relevant models of human heart tissue. Existing myocardial cell constructs—such as organoids or spheroids—often fail to mimic the intricate structure and function of real cardiac tissue, limiting their effectiveness in research and therapeutic applications. To solve this, SONOCRAFT combines rapid volumetric 3D bioprinting with ultrasonic particle manipulation, enabling the formation of aligned, centimetre-scale cardiac constructs embedded within hydrogels. These constructs feature built-in vasculature to maintain long-term tissue health through efficient nutrient and oxygen delivery. SONOCRAFT is more than a tool—it’s a platform for building the future of cardiovascular research, offering scalable, reproducible, and high-fidelity cardiac models that simulate in vivo conditions more accurately than ever before.