Sovicell

Sovicell offers products and services for preclinical pharmaceutical research. We offer tissue binding and tissue distribution assays as well as membrane permeability assays that provide reliable results in less than 30 minutes. Assays include: • Brain tissue binding • Blood-brain barrier penetration • Liver microsomal binding • Intestinal absorption • Volume of distribution prediction • Plasma protein binding (sticky, hardly soluble drugs and peptides) • Plasma protein binding (screening) • AAG/AGP binding (dissociation constant determination) • HSA binding (dissociation constant determination) Also, Sovicell offers boutique services for plasma protein binding studies to support reliable dose finding for first in man studies. We prove state of the art services for plasma binding and plasma displacement, including controls for plasma instability, recovery and matrix effects in LC-MS/MS.