Spero Therapeutics

Spero Therapeutics company information, Employees & Contact Information

We are a multi-asset, clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant ("MDR”) bacterial infections with high unmet need. Our pipeline consists of three mid to late-stage clinical assets. Tebipenem HBr is in Phase 3 development, with the potential to be the first broad-spectrum oral carbapenem to treat complicated urinary tract infections ("cUTIs”) including acute pyelonephritis, caused by certain microorganisms, in adult patients. SPR206 is a Phase 2 ready IV-administered antibiotic being developed as an innovative option to treat MDR Gram-negative bacterial infections in the hospital setting. SPR720, the development of which was recently suspended, is a Phase 2 investigational oral agent for the first-line treatment of nontuberculous mycobacterial ("NTM”) pulmonary disease, a rare disease. As previously disclosed, following the SPR720 program suspension, we are evaluating other potential paths forward as the remaining data are collected and analyzed.

Company Details

Employees
47
Founded
-
Address
675 Massachusetts Ave,
Phone
+1 857 242 1600
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
HQ
Cambridge, MA
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News

Spero Therapeutics Announces Presentations on Tebipenem Hbr at IDWeek - GlobeNewswire

Spero Therapeutics Announces Presentations on Tebipenem Hbr at IDWeek GlobeNewswire

Spero Therapeutics to Report Second Quarter 2025 Financial Results and Provide Business Update on Tuesday, August 12, 2025 - Yahoo Finance

Spero Therapeutics to Report Second Quarter 2025 Financial Results and Provide Business Update on Tuesday, August 12, 2025 Yahoo Finance

Spero Q2 2025 Earnings: Rare Disease and MDR Treatment Pipeline Updates Coming August 12 - Stock Titan

Spero Q2 2025 Earnings: Rare Disease and MDR Treatment Pipeline Updates Coming August 12 Stock Titan

Spero Therapeutics Announces Second Quarter 2025 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces Second Quarter 2025 Operating Results and Provides a Business Update GlobeNewswire

Breakthrough UTI Treatment Success: First-Ever Oral Carbapenem Shows Early Phase 3 Win in $6B Market - Stock Titan

Breakthrough UTI Treatment Success: First-Ever Oral Carbapenem Shows Early Phase 3 Win in $6B Market Stock Titan

PIVOT-PO phase III study for tebipenem HBr stopped early for efficacy following review by Independent Data Monitoring Committee - GSK

PIVOT-PO phase III study for tebipenem HBr stopped early for efficacy following review by Independent Data Monitoring Committee GSK

Spero Therapeutics Appoints Esther Rajavelu as CEO - citybiz

Spero Therapeutics Appoints Esther Rajavelu as CEO citybiz

Spero Therapeutics and GSK Announce Positive Results for Oral Tebipenem HBr in Phase 3 Trial for Complicated Urinary Tract Infections - Quiver Quantitative

Spero Therapeutics and GSK Announce Positive Results for Oral Tebipenem HBr in Phase 3 Trial for Complicated Urinary Tract Infections Quiver Quantitative

Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive Officer - GlobeNewswire

Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive Officer GlobeNewswire

GSK and Spero Therapeutics announce exclusive licence agreement for tebipenem HBr, a late-stage antibiotic that may treat complicated urinary tract infections - GSK

GSK and Spero Therapeutics announce exclusive licence agreement for tebipenem HBr, a late-stage antibiotic that may treat complicated urinary tract infections GSK

Spero Therapeutics to Report First Quarter 2025 Financial - GlobeNewswire

Spero Therapeutics to Report First Quarter 2025 Financial GlobeNewswire

Phase 3 PIVOT-PO: Spero Therapeutics to present oral tebipenem HBr cUTI data at IDWeek Oct 20 - Stock Titan

Phase 3 PIVOT-PO: Spero Therapeutics to present oral tebipenem HBr cUTI data at IDWeek Oct 20 Stock Titan

Spero's Oral Antibiotic Shows Promise in Reducing Hospital Stays for UTI Patients - Stock Titan

Spero's Oral Antibiotic Shows Promise in Reducing Hospital Stays for UTI Patients Stock Titan

Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study - GlobeNewswire

Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Provides Business Update and Announces Interim Leadership Changes - GlobeNewswire

Spero Therapeutics Provides Business Update and Announces Interim Leadership Changes GlobeNewswire

Spero Therapeutics to Report First Quarter 2024 Financial - GlobeNewswire

Spero Therapeutics to Report First Quarter 2024 Financial GlobeNewswire

Spero Therapeutics to Present at Cowen’s 44th Annual Healthcare Conference - GlobeNewswire

Spero Therapeutics to Present at Cowen’s 44th Annual Healthcare Conference GlobeNewswire

Spero Therapeutics Appoints Sath Shukla as CEO - citybiz

Spero Therapeutics Appoints Sath Shukla as CEO citybiz

Spero (NASDAQ: SPRO) pivotal trial stopped early, noninferiority met, Q4 2025 filing - Stock Titan

Spero (NASDAQ: SPRO) pivotal trial stopped early, noninferiority met, Q4 2025 filing Stock Titan

Spero Therapeutics Announces First Quarter 2024 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces First Quarter 2024 Operating Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Announces SPR720 Phase 2a Interim Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces SPR720 Phase 2a Interim Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2023 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2023 Operating Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Announces New Strategic Direction Focusing on Advancing Promising Clinical-Stage Pipeline - GlobeNewswire

Spero Therapeutics Announces New Strategic Direction Focusing on Advancing Promising Clinical-Stage Pipeline GlobeNewswire

Spero Therapeutics Receives Complete Response Letter from - GlobeNewswire

Spero Therapeutics Receives Complete Response Letter from GlobeNewswire

Spero Therapeutics Announces Closing of Exclusive License Agreement with GSK for Tebipenem HBr - GlobeNewswire

Spero Therapeutics Announces Closing of Exclusive License Agreement with GSK for Tebipenem HBr GlobeNewswire

FDA denies Spero's UTI treatment - Healio

FDA denies Spero's UTI treatment Healio

Spero Therapeutics Announces $40 Million Equity Investment from Pfizer Inc. and Licensing Agreement for SPR206 - GlobeNewswire

Spero Therapeutics Announces $40 Million Equity Investment from Pfizer Inc. and Licensing Agreement for SPR206 GlobeNewswire

Spero Therapeutics Enters Into a Non-Dilutive Revenue - GlobeNewswire

Spero Therapeutics Enters Into a Non-Dilutive Revenue GlobeNewswire

Spero Therapeutics Announces $40M Equity Investment from Pfizer - citybiz

Spero Therapeutics Announces $40M Equity Investment from Pfizer citybiz

Spero Therapeutics Announces Positive Topline Results from - GlobeNewswire

Spero Therapeutics Announces Positive Topline Results from GlobeNewswire

Spero Therapeutics Signs License Agreement with Everest - GlobeNewswire

Spero Therapeutics Signs License Agreement with Everest GlobeNewswire

Spero Therapeutics Licenses Exclusive Rights to SPR994, a Novel Oral Carbapenem Being Studied for Use in Adults - GlobeNewswire

Spero Therapeutics Licenses Exclusive Rights to SPR994, a Novel Oral Carbapenem Being Studied for Use in Adults GlobeNewswire

Spero Therapeutics Launches Initial Public Offering - GlobeNewswire

Spero Therapeutics Launches Initial Public Offering GlobeNewswire

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