Spero Therapeutics

Spero Therapeutics company information, Employees & Contact Information

Updated June 2026

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Spero Therapeutics is a Biotechnology Research company and founded in 2013. It has approximately 47 employees on record. Contact data was last refreshed in June 2026. Find Spero Therapeutics's verified employee emails, phone numbers, headquarters address, and key decision makers below.

We are a multi-asset, clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant ("MDR”) bacterial infections with high unmet need. Our pipeline consists of three mid to late-stage clinical assets. Tebipenem HBr is in Phase 3 development, with the potential to be the first broad-spectrum oral carbapenem to treat complicated urinary tract infections ("cUTIs”) including acute pyelonephritis, caused by certain microorganisms, in adult patients. SPR206 is a Phase 2 ready IV-administered antibiotic being developed as an innovative option to treat MDR Gram-negative bacterial infections in the hospital setting. SPR720, the development of which was recently suspended, is a Phase 2 investigational oral agent for the first-line treatment of nontuberculous mycobacterial ("NTM”) pulmonary disease, a rare disease. As previously disclosed, following the SPR720 program suspension, we are evaluating other potential paths forward as the remaining data are collected and analyzed.

Company Details

Employees
47
Founded
2013
Address
675 Massachusetts Ave,
Phone
+1 857 242 1600
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
HQ
Cambridge, MA
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Spero Therapeutics Questions

News

Spero Therapeutics Announces Presentations on Tebipenem Hbr at IDWeek - GlobeNewswire

Spero Therapeutics Announces Presentations on Tebipenem Hbr at IDWeek GlobeNewswire

Spero Therapeutics to Report Second Quarter 2025 Financial Results and Provide Business Update on Tuesday, August 12, 2025 - Yahoo Finance

Spero Therapeutics to Report Second Quarter 2025 Financial Results and Provide Business Update on Tuesday, August 12, 2025 Yahoo Finance

Spero Q2 2025 Earnings: Rare Disease and MDR Treatment Pipeline Updates Coming August 12 - Stock Titan

Spero Q2 2025 Earnings: Rare Disease and MDR Treatment Pipeline Updates Coming August 12 Stock Titan

Spero Therapeutics Announces Second Quarter 2025 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces Second Quarter 2025 Operating Results and Provides a Business Update GlobeNewswire

Breakthrough UTI Treatment Success: First-Ever Oral Carbapenem Shows Early Phase 3 Win in $6B Market - Stock Titan

Breakthrough UTI Treatment Success: First-Ever Oral Carbapenem Shows Early Phase 3 Win in $6B Market Stock Titan

PIVOT-PO phase III study for tebipenem HBr stopped early for efficacy following review by Independent Data Monitoring Committee - GSK

PIVOT-PO phase III study for tebipenem HBr stopped early for efficacy following review by Independent Data Monitoring Committee GSK

Spero Therapeutics Appoints Esther Rajavelu as CEO - citybiz

Spero Therapeutics Appoints Esther Rajavelu as CEO citybiz

Spero Therapeutics and GSK Announce Positive Results for Oral Tebipenem HBr in Phase 3 Trial for Complicated Urinary Tract Infections - Quiver Quantitative

Spero Therapeutics and GSK Announce Positive Results for Oral Tebipenem HBr in Phase 3 Trial for Complicated Urinary Tract Infections Quiver Quantitative

Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive Officer - GlobeNewswire

Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive Officer GlobeNewswire

GSK and Spero Therapeutics announce exclusive licence agreement for tebipenem HBr, a late-stage antibiotic that may treat complicated urinary tract infections - GSK

GSK and Spero Therapeutics announce exclusive licence agreement for tebipenem HBr, a late-stage antibiotic that may treat complicated urinary tract infections GSK

Spero Therapeutics to Report First Quarter 2025 Financial - GlobeNewswire

Spero Therapeutics to Report First Quarter 2025 Financial GlobeNewswire

Phase 3 PIVOT-PO: Spero Therapeutics to present oral tebipenem HBr cUTI data at IDWeek Oct 20 - Stock Titan

Phase 3 PIVOT-PO: Spero Therapeutics to present oral tebipenem HBr cUTI data at IDWeek Oct 20 Stock Titan

Spero's Oral Antibiotic Shows Promise in Reducing Hospital Stays for UTI Patients - Stock Titan

Spero's Oral Antibiotic Shows Promise in Reducing Hospital Stays for UTI Patients Stock Titan

Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study - GlobeNewswire

Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Provides Business Update and Announces Interim Leadership Changes - GlobeNewswire

Spero Therapeutics Provides Business Update and Announces Interim Leadership Changes GlobeNewswire

Spero Therapeutics to Report First Quarter 2024 Financial - GlobeNewswire

Spero Therapeutics to Report First Quarter 2024 Financial GlobeNewswire

Spero Therapeutics to Present at Cowen’s 44th Annual Healthcare Conference - GlobeNewswire

Spero Therapeutics to Present at Cowen’s 44th Annual Healthcare Conference GlobeNewswire

Spero Therapeutics Appoints Sath Shukla as CEO - citybiz

Spero Therapeutics Appoints Sath Shukla as CEO citybiz

Spero (NASDAQ: SPRO) pivotal trial stopped early, noninferiority met, Q4 2025 filing - Stock Titan

Spero (NASDAQ: SPRO) pivotal trial stopped early, noninferiority met, Q4 2025 filing Stock Titan

Spero Therapeutics Announces First Quarter 2024 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces First Quarter 2024 Operating Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Announces SPR720 Phase 2a Interim Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces SPR720 Phase 2a Interim Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2023 Operating Results and Provides a Business Update - GlobeNewswire

Spero Therapeutics Announces Fourth Quarter and Full Year 2023 Operating Results and Provides a Business Update GlobeNewswire

Spero Therapeutics Announces New Strategic Direction Focusing on Advancing Promising Clinical-Stage Pipeline - GlobeNewswire

Spero Therapeutics Announces New Strategic Direction Focusing on Advancing Promising Clinical-Stage Pipeline GlobeNewswire

Spero Therapeutics Receives Complete Response Letter from - GlobeNewswire

Spero Therapeutics Receives Complete Response Letter from GlobeNewswire

Spero Therapeutics Announces Closing of Exclusive License Agreement with GSK for Tebipenem HBr - GlobeNewswire

Spero Therapeutics Announces Closing of Exclusive License Agreement with GSK for Tebipenem HBr GlobeNewswire

FDA denies Spero's UTI treatment - Healio

FDA denies Spero's UTI treatment Healio

Spero Therapeutics Announces $40 Million Equity Investment from Pfizer Inc. and Licensing Agreement for SPR206 - GlobeNewswire

Spero Therapeutics Announces $40 Million Equity Investment from Pfizer Inc. and Licensing Agreement for SPR206 GlobeNewswire

Spero Therapeutics Enters Into a Non-Dilutive Revenue - GlobeNewswire

Spero Therapeutics Enters Into a Non-Dilutive Revenue GlobeNewswire

Spero Therapeutics Announces $40M Equity Investment from Pfizer - citybiz

Spero Therapeutics Announces $40M Equity Investment from Pfizer citybiz

Spero Therapeutics Announces Positive Topline Results from - GlobeNewswire

Spero Therapeutics Announces Positive Topline Results from GlobeNewswire

Spero Therapeutics Signs License Agreement with Everest - GlobeNewswire

Spero Therapeutics Signs License Agreement with Everest GlobeNewswire

Spero Therapeutics Licenses Exclusive Rights to SPR994, a Novel Oral Carbapenem Being Studied for Use in Adults - GlobeNewswire

Spero Therapeutics Licenses Exclusive Rights to SPR994, a Novel Oral Carbapenem Being Studied for Use in Adults GlobeNewswire

Spero Therapeutics Launches Initial Public Offering - GlobeNewswire

Spero Therapeutics Launches Initial Public Offering GlobeNewswire

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