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SYNAPTIC is an IT company focused on delivering innovative software and hardware solutions to solve problems by using emerging technologies and trends. We believe our strengths resides in our Agile Development Methodology, employees and Client focused business.

Company Details

Employees
15
Founded
-
Address
Avenida Maríano Sánchez Fontecilla 368, Las Condes,santiago Metropolitan 7550000,chile
Phone
+56 2 2928 9740
Email
in****@****ptic.cl
Industry
It Services And It Consulting
NAICS
Computer Systems Design and Related Services
Other Computer Related Services
Keywords
IT Consulting.
HQ
Las Condes, Santiago Metropolitan
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Synaptic It Questions

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Glial reactivity correlates with synaptic dysfunction across aging and Alzheimer’s disease - Nature

Glial reactivity correlates with synaptic dysfunction across aging and Alzheimer’s disease Nature

Selective regulation of corticostriatal synapses by astrocytic phagocytosis - Nature

Selective regulation of corticostriatal synapses by astrocytic phagocytosis Nature

Distinctive synaptic structural motifs link excitatory retinal interneurons to diverse postsynaptic partner types - ScienceDirect.com

Distinctive synaptic structural motifs link excitatory retinal interneurons to diverse postsynaptic partner types ScienceDirect.com

Ammonium chloride reduces excitatory synaptic transmission onto CA1 pyramidal neurons of mouse organotypic slice cultures - Frontiers

Ammonium chloride reduces excitatory synaptic transmission onto CA1 pyramidal neurons of mouse organotypic slice cultures Frontiers

A small pool of vesicles maintains synaptic activity in vivo - PNAS

A small pool of vesicles maintains synaptic activity in vivo PNAS

PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exocytosis and endocytosis - Nature

PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exocytosis and endocytosis Nature

Active cortical networks promote shunting fast synaptic inhibition in vivo - ScienceDirect.com

Active cortical networks promote shunting fast synaptic inhibition in vivo ScienceDirect.com

Short-term ionic plasticity at GABAergic synapses - Frontiers

Short-term ionic plasticity at GABAergic synapses Frontiers

Deletion of CASK in mice is lethal and impairs synaptic function - PNAS

Deletion of CASK in mice is lethal and impairs synaptic function PNAS

GABAergic neuron-to-glioma synapses in diffuse midline gliomas - Nature

GABAergic neuron-to-glioma synapses in diffuse midline gliomas Nature

Pre- and post-synaptic switches of GABA actions associated with Cl− homeostatic changes are induced in the spinal nucleus of the trigeminal nerve in a rat model of trigeminal neuropathic pain - ScienceDirect.com

Pre- and post-synaptic switches of GABA actions associated with Cl− homeostatic changes are induced in the spinal nucleus of the trigeminal nerve in a rat model of trigeminal neuropathic pain ScienceDirect.com

Inhibitory synaptic plasticity: spike timing-dependence and putative network function - Frontiers

Inhibitory synaptic plasticity: spike timing-dependence and putative network function Frontiers

Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission - ScienceDirect.com

Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission ScienceDirect.com

Intracellular Trafficking Mechanisms of Synaptic Dysfunction in Alzheimer’s Disease - Frontiers

Intracellular Trafficking Mechanisms of Synaptic Dysfunction in Alzheimer’s Disease Frontiers

Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization - Nature

Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization Nature

Vesicular Glutamate Transporter Expression Ensures High-Fidelity Synaptic Transmission at the Calyx of Held Synapses - ScienceDirect.com

Vesicular Glutamate Transporter Expression Ensures High-Fidelity Synaptic Transmission at the Calyx of Held Synapses ScienceDirect.com

Synaptic-like transmission between neural axons and arteriolar smooth muscle cells drives cerebral neurovascular coupling - Nature

Synaptic-like transmission between neural axons and arteriolar smooth muscle cells drives cerebral neurovascular coupling Nature

receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl - Nature

receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl Nature

A synaptic signal for novelty processing in the hippocampus - Nature

A synaptic signal for novelty processing in the hippocampus Nature

Synaptic Glutamate Release Is Modulated by the Na+-Driven Cl−/HCO3− Exchanger Slc4a8 - Journal of Neuroscience

Synaptic Glutamate Release Is Modulated by the Na+-Driven Cl−/HCO3− Exchanger Slc4a8 Journal of Neuroscience

Synaptic Transfer between Rod and Cone Pathways Mediated by AII Amacrine Cells in the Mouse Retina - ScienceDirect.com

Synaptic Transfer between Rod and Cone Pathways Mediated by AII Amacrine Cells in the Mouse Retina ScienceDirect.com

Prefrontal microglia deficiency during adolescence disrupts adult cognitive functions and synaptic structures: A follow-up study in female mice - ScienceDirect.com

Prefrontal microglia deficiency during adolescence disrupts adult cognitive functions and synaptic structures: A follow-up study in female mice ScienceDirect.com

Synaptic Vesicle Recycling and the Endolysosomal System: A Reappraisal of Form and Function - Frontiers

Synaptic Vesicle Recycling and the Endolysosomal System: A Reappraisal of Form and Function Frontiers

Ammonium chloride alters neuronal excitability and synaptic vesicle release - Nature

Ammonium chloride alters neuronal excitability and synaptic vesicle release Nature

Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles - Nature

Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles Nature

Dynamics and conditions for inhibitory synaptic current to induce bursting and spreading depolarization in pyramidal neurons - Nature

Dynamics and conditions for inhibitory synaptic current to induce bursting and spreading depolarization in pyramidal neurons Nature

Presynaptic nanoscale components of retrograde synaptic signaling - Science | AAAS

Presynaptic nanoscale components of retrograde synaptic signaling Science | AAAS

Serine 937 phosphorylation enhances KCC2 activity and strengthens synaptic inhibition - Nature

Serine 937 phosphorylation enhances KCC2 activity and strengthens synaptic inhibition Nature

Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models - Frontiers

Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models Frontiers

Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation - Journal of Neuroscience

Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation Journal of Neuroscience

The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms - Frontiers

The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms Frontiers

Normalized unitary synaptic signaling of the hippocampus and entorhinal cortex predicted by deep learning of experimental recordings - Nature

Normalized unitary synaptic signaling of the hippocampus and entorhinal cortex predicted by deep learning of experimental recordings Nature

CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation - Nature

CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation Nature

Mimicking associative learning using an ion-trapping non-volatile synaptic organic electrochemical transistor - Nature

Mimicking associative learning using an ion-trapping non-volatile synaptic organic electrochemical transistor Nature

Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory - Frontiers

Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory Frontiers

Handling accumulated internal Cl− at inhibitory synapses - Nature Neuroscience - Nature

Handling accumulated internal Cl− at inhibitory synapses - Nature Neuroscience Nature

Differential pH Dynamics in Synaptic Vesicles From Intact Glutamatergic and GABAergic Synapses - Frontiers

Differential pH Dynamics in Synaptic Vesicles From Intact Glutamatergic and GABAergic Synapses Frontiers

Epsin1 modulates synaptic vesicle retrieval capacity at CNS synapses - Nature

Epsin1 modulates synaptic vesicle retrieval capacity at CNS synapses Nature

Synaptic vesicle pools are a major hidden resting metabolic burden of nerve terminals - Science | AAAS

Synaptic vesicle pools are a major hidden resting metabolic burden of nerve terminals Science | AAAS

Ion transport and regulation in a synaptic vesicle glutamate transporter - Science | AAAS

Ion transport and regulation in a synaptic vesicle glutamate transporter Science | AAAS

VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses - Nature

VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses Nature

Tau association with synaptic vesicles causes presynaptic dysfunction - Nature

Tau association with synaptic vesicles causes presynaptic dysfunction Nature

The Neural Circuits and Synaptic Mechanisms Underlying Motor Initiation in C. elegans - ScienceDirect.com

The Neural Circuits and Synaptic Mechanisms Underlying Motor Initiation in C. elegans ScienceDirect.com

Depolarizing GABA/glycine synaptic events switch from excitation to inhibition during frequency increases - Nature

Depolarizing GABA/glycine synaptic events switch from excitation to inhibition during frequency increases Nature

Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression - Nature

Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression Nature

Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms - Nature

Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms Nature

Diverse synaptic plasticity mechanisms orchestrated to form and retrieve memories in spiking neural networks - Nature

Diverse synaptic plasticity mechanisms orchestrated to form and retrieve memories in spiking neural networks Nature

Activity-Induced Synaptic Capture and Exocytosis of the Neuronal Serine Protease Neurotrypsin - Journal of Neuroscience

Activity-Induced Synaptic Capture and Exocytosis of the Neuronal Serine Protease Neurotrypsin Journal of Neuroscience

Neuroligin-2 Deletion Selectively Decreases Inhibitory Synaptic Transmission Originating from Fast-Spiking but Not from Somatostatin-Positive Interneurons - Journal of Neuroscience

Neuroligin-2 Deletion Selectively Decreases Inhibitory Synaptic Transmission Originating from Fast-Spiking but Not from Somatostatin-Positive Interneurons Journal of Neuroscience

Release activity-dependent control of vesicle endocytosis by the synaptic adhesion molecule N-cadherin - Nature

Release activity-dependent control of vesicle endocytosis by the synaptic adhesion molecule N-cadherin Nature

Synaptic plasticity by antidromic firing during hippocampal network oscillations - PNAS

Synaptic plasticity by antidromic firing during hippocampal network oscillations PNAS

Synaptic GABA release prevents GABA transporter type-1 reversal during excessive network activity - Nature

Synaptic GABA release prevents GABA transporter type-1 reversal during excessive network activity Nature

All‐Solid‐State Synaptic Transistor with Ultralow Conductance for Neuromorphic Computing - Wiley Online Library

All‐Solid‐State Synaptic Transistor with Ultralow Conductance for Neuromorphic Computing Wiley Online Library

Light-Evoked Excitatory and Inhibitory Synaptic Inputs to ON and OFF α Ganglion Cells in the Mouse Retina - Journal of Neuroscience

Light-Evoked Excitatory and Inhibitory Synaptic Inputs to ON and OFF α Ganglion Cells in the Mouse Retina Journal of Neuroscience

Synaptic Currents Generating the Inhibitory Surround of Ganglion Cells in the Mammalian Retina - Journal of Neuroscience

Synaptic Currents Generating the Inhibitory Surround of Ganglion Cells in the Mammalian Retina Journal of Neuroscience

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