Synlogic

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Synlogic is a clinical-stage biotechnology company advancing novel, oral, non-systemically absorbed biotherapeutics to transform the care of serious diseases in need of new treatment options. The Company’s late-stage pipeline is focused on rare metabolic diseases, led by labafenogene marselecobac (SYNB1934), currently being studied as a potential treatment for phenylketonuria (PKU) in Synpheny-3, a global, pivotal Phase 3 study. Additional product candidates address diseases including homocystinuria (HCU), enteric hyperoxaluria, gout, and cystinuria. This pipeline is fueled by the Synthetic Biotic platform, which applies precision genetic engineering to well-characterized probiotics. This enables Synlogic to create GI-restricted, oral medicines designed to consume or modify disease-specific metabolites – an approach well suited for PKU and HCU, both inborn errors of metabolism, as well as other disorders in which the disease–specific metabolites transit through the GI tract, providing validated targets for these Synthetic Biotics. Research activities include a partnership with Roche focused on inflammatory bowel disease (IBD), and a collaboration with Ginkgo Bioworks in synthetic biology, which has contributed to two pipeline programs to date. For more information, please visit www.synlogictx.com

Company Details

Employees
21
Founded
-
Address
301 Binney St, Cambridge,massachusetts 02142,united States
Phone
(617)401-9975
Email
in****@****ctx.com
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
HQ
Cambridge, Massachusetts
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News

Synlogic probiotics turn up the heat on cancer and metabolic disease - Nature

Synlogic probiotics turn up the heat on cancer and metabolic disease Nature

Synlogic Appoints Patricia N. Hurter, Ph.D. to Board of Directors - SynBioBeta

Synlogic Appoints Patricia N. Hurter, Ph.D. to Board of Directors SynBioBeta

Synlogic Announces Pricing of $21.0 Million Underwritten Public Offering - Stock Titan

Synlogic Announces Pricing of $21.0 Million Underwritten Public Offering Stock Titan

Using Synthetic Biology To Develop Novel Biotherapeutics - BioProcess International

Using Synthetic Biology To Develop Novel Biotherapeutics BioProcess International

Synlogic Announces Initiation of Synpheny-3 Global, Pivotal - GlobeNewswire

Synlogic Announces Initiation of Synpheny-3 Global, Pivotal GlobeNewswire

Trial Investigating Treatment for Hyperammonemia in Cirrhosis Discontinued - Medical Professionals Reference

Trial Investigating Treatment for Hyperammonemia in Cirrhosis Discontinued Medical Professionals Reference

Contact - The Lethbridge Herald - News and Sports from around Lethbridge - FinancialContent

Contact - The Lethbridge Herald - News and Sports from around Lethbridge FinancialContent

Synlogic Appoints David Hava, Ph.D., as Chief Scientific Officer - SynBioBeta

Synlogic Appoints David Hava, Ph.D., as Chief Scientific Officer SynBioBeta

Synlogic Appoints Dr. Michael Burgess to its Board of Directors - SynBioBeta

Synlogic Appoints Dr. Michael Burgess to its Board of Directors SynBioBeta

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