Telethon Institute of Genetics and Medicine (TIGEM)

TIGEM is a leading research institute dedicated to uncovering the molecular mechanisms of rare genetic diseases and translating these discoveries into innovative therapies. As one of Italy’s most prominent centers for biomedical research, TIGEM plays a pivotal role in the international scientific landscape, particularly in the fields of lysosomal storage disorders, membrane trafficking defects, metabolic liver diseases, and inherited eye conditions. Founded and supported by Fondazione Telethon, TIGEM is at the heart of the foundation’s scientific mission to develop new therapeutic approaches for rare genetic disorders. Its unique funding framework empowers researchers to pursue long-term, high-impact projects that are often difficult to support in conventional research environments. Our Mission: 🔬 Advance fundamental, translational, and clinical research that sets new standards of excellence in the field of rare genetic diseases 💊 Accelerate the development of effective therapies, often in partnership with industry, to ensure that scientific breakthroughs reach patients 👩🔬 Train the next generation of scientists and clinicians committed to transforming the future of rare disease treatment Located in a strikingly renovated Olivetti industrial building in Pozzuoli, near Naples, TIGEM’s 5,000 m² campus features modern open-space labs, a large auditorium, and 10 cutting-edge core facilities supporting 26 research groups and over 270 scientists from around the world. TIGEM’s track record includes: 18 European Research Council (ERC) grants 14 EU cooperative research projects coordinated more than 6000 papers published in peer reviewd journals 3 spinoffs around 30 patents TIGEM is more than a research institute—it's a hub of innovation, a talent incubator, and a driver of therapeutic development for some of the world’s most challenging and underserved diseases. 🌐 Learn more: https://www.tigem.it