Ultimate Medicine AG

Ultimate Medicine develops novel small molecules to improve cognitive function and treat dementia by targeting a unique gut-derived metabolite that increases with age and contributes to cognitive decline. Our approach offers a first-in-class mechanism to restore brain health by intervening at the gut-brain axis. Ultimate Medicine AG is a Swiss preclinical pharmaceutical company pioneering an innovative oral treatment for age-related cognitive disorders, including Alzheimer's disease. Our approach uniquely targets a key disease pathway that current therapies have overlooked, complementing existing research on amyloid-β and tau. With decades of pharmaceutical development and commercialization experience, our team is dedicated to developing a treatment that may potentially slow or halt cognitive decline. Supported by peer-reviewed research in Nature Aging, our companion diagnostic program is designed to optimize patient selection, de-risk clinical development, and enable precision targeting in an underserved and rapidly growing dementia market.