Valerio Therapeutics is a clinical-stage biotechnology company based in France and the US that develops new drugs by targeting tumor DNA functions through unique mechanisms of action in the field of DNA Damage Response (DDR).
DDR consists of a network of cellular pathways that detect, report and repair DNA damage. Applied to oncology, this new field of research aims to weaken or block the ability of tumor cells to repair damage to their DNA, either naturally or under the effect of cytotoxic treatments.
Focusing exclusively on intracellular DNA-binding targets, we design and develop first-in-class treatments for oncology and inflammatory diseases precision therapeutics from preclinical (translational) research to human clinical proof-of-concept studies. It thus leads its programs to the most value-creating and attractive inflection points for potential partners.
The Company's portfolio is based on platON™, Valerio Therapeutic's decoy oligonucleotide platform.
PlatON™ is intended to generate new compounds based on an unparalleled DDR decoy mechanism and capitalizing on the expertise the Company has developed on this type of oligonucleotides.
The Company's portfolio includes:
- AsiDNA™, a first-in-class product interfering with tumor DNA break repair, based on a decoy agonist mechanism, unmatched in the DDR field, which could, among other things, combat tumor resistance. AsiDNA™ is in clinical development in several trials, in combination with PARP inhibitors or in combination with radiation therapy.
- A new family of compounds are positioned as a new-generation PARP agonists that are designed not to induce resistance and to activate the immune response. VIO-01, is currently being optimized in a preclinical phase.
The Company is convinced of the significant therapeutic potential of its technology and the disruptive innovation it represents, which could pave the way for a new paradigm in cancer and inflammatory disease treatments.
Company Details
- Employees
- 48
- Founded
- -
- Address
- 49 Boulevard Du Général Martial Valin, Paris,75015,france
- Industry
- Pharmaceutical Manufacturing
- NAICS
-
Pharmaceutical and Medicine ManufacturingMedicinal and Botanical ManufacturingPharmaceutical Preparation ManufacturingIn-Vitro Diagnostic Substance ManufacturingBiological Product (except Diagnostic) Manufacturing
- Website
- https://valeriotx.com
- Keywords
- Oncology, DNA Damage Response, Epigenetics, Translational research, Partnering, M&A, Licensing, DNA repair, HDAC, Cancer, oligonucleotide, DDR, DNA Decoy.
- HQ
- Paris
Valerio Therapeutics Questions
Valerio Therapeutics's website is https://valeriotx.com
Valerio Therapeutics's LinkedIn profile is https://fr.linkedin.com/company/valerio-tx
Valerio Therapeutics has
48 employees.
View email and phone details for 48
employees at Valerio Therapeutics.
Valerio Therapeutics's industry is
Pharmaceutical Manufacturing
Valerio Therapeutics's top competitors are
Nanobiotix,
Ose Immunotherapeutics,
Cellectis,
Mnemo Therapeutics,
Owkin,
Abivax,
Emglev Therapeutics,
Institut Curie,
Vertex Pharmaceuticals,
Sironax.
Valerio Therapeutics's categories are Pharmaceutical Manufacturing
Valerio Therapeutics's founding year is 2014
