VIB Switch Laboratory

Switch Laboratory is an independent research group supported by the Flanders Interuniversity Institute for Biotechnology (VIB), located at the Free University of Brussels (VUB). Our research is geared on 3 topics that closely interact: 1. protein (mis)folding, aggregation and amyloidosis with a particular attention for aggregation gatekeepers 2. protein dynamics and signal transduction: how do conformational fluctuations of the native state achieve signal transduction and allostery? 3. the effect of SNPs on the molecular phenotype of proteins: how does human genetic variability affect protein conformation and function?