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) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII Nature

An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo ScienceDirect.com

/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo Nature

Targeted protein degraders of SARS-CoV-2 Mpro are more active than enzymatic inhibition alone with activity against nirmatrelvir resistant virus | Communications Medicine Nature

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro Science | AAAS

Covalent small-molecule inhibitors of SARS-CoV-2 Mpro: Insights into their design, classification, biological activity, and binding interactions ScienceDirect.com

Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease ScienceDirect.com

Max Property (MPRO) Kini Hadir di INDODAX! INDODAX

inhibition by benzisoselenazolones and diselenides Nature

) by repurposing/designing drug-like substances and utilizing nature’s toolbox of bioactive compounds ScienceDirect.com

Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay Nature

responds to oxidation by forming disulfide and NOS/SONOS bonds Nature

inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron Nature

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors Nature

causes microvascular brain pathology by cleaving NEMO in brain endothelial cells Nature

active site cavity revealed by room temperature X-ray crystallography Nature

SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging | Nature Chemical Biology Nature