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PhoenixBio established its proprietary chimeric mouse model, the PXB-mouse®, with a highly humanized liver through years of research and development. With the addition of fresh, isolated human hepatocytes, PXB-cells®, the applications of our products and study services are as wide-ranging as our clients’ research goals.
The PXB-mouse animal background (cDNA-uPA/SCID) makes for a robust, consistent model that maintains up to 95% stable human hepatocyte engraftment. The reconstituted humanized liver features structural and biological characteristics commonly observed in normal human livers.
The model has proven to be a world-wide gold standard for Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) research, but usage is expanding in the fields of:
. Drug Metabolism and Pharmacokinetics,
· Human Specific Hepatotoxicity,
· Oligonucleotide and Gene-based Therapeutics,
· HBV & HBV/HDV,
· NASH/NAFLD,
· Other human liver-related research fields.
PXB-cells® are approximately 95% pure human hepatocytes freshly isolated from the PXB-mouse®. They feature long-term stability of up to 40 days, and allow for consistent supply from the same donor. One unique feature of PXB-cells® and PXB-mice is the ability to directly compare in vitro and in vitro data from the same human donor.
With over 300 scientific publications to its credit, the PXB-mouse is the world’s most widely used chimeric mouse model with a humanized liver. A high replacement index, lifespan of up to 2 years, and no secondary drug to maintain mouse liver injury means that your data can translate better to humans than ever before.
Please visit our website at https://www.phoenixbio.com/ to learn more about our model and inquire about our offered products and services.
Company Details
- Employees
- 24
- Founded
- -
- Address
- 3-4-1, Kagamiyama, Higashi-Hiroshima City,hiroshima 739-0046,japan
- Industry
- Biotechnology Research
- Website
- phoenixbio.co.jp
- Keywords
- Biotechnology, Contract Research, Study Services, Project Management, Logistics, Drug Development, Drug metabolism, Safety, Toxicity, Pharmaceuticals, Efficacy testing, Humanized model, Hepatocytes.
- HQ
- Higashi-Hiroshima City, Hiroshima
Phoenixbio Questions
PhoenixBio's website is phoenixbio.co.jp
PhoenixBio's LinkedIn profile is https://www.linkedin.com/company/phoenixbio
PhoenixBio has
24 employees.
View email and phone details for 24
employees at PhoenixBio.
PhoenixBio's industry is
Biotechnology Research
PhoenixBio's top competitors are
Onesoftware Powered By Flexschema,
Yecuris Corporation,
Molscreen,
Fenfyre,
Research Diets, Inc.,
Btig,
Recursion,
Glyco Biologics Inc.,
Orbital Therapeutics,
Kmt Hepatech, Inc. - Phoenixbio Group.
PhoenixBio's categories are Biotechnology Research
PhoenixBio's founding year is 2002
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Top PhoenixBio Employees
-
Yoshinari Miyata
Chief Innovation Officer At Phoenixbio Usa
Ann Arbor, Michigan, United States, United States3umich.edu, gmail.com, umich.edu -
Chise Mukaidani
Phoenixbio Co., Ltd. - Executive Director, Research And Development Department
Hiroshima, Japan, Japan -
TAKASHI SHIMADA
President And Ceo At Phoenixbio Co., Ltd
Hiroshima, Japan, Japan1phoenixbio.co.jp -
Li Na, PhD, QIHC (CM)
Phd Scientist | Expert In Biological Assays & Preclinical Research | Supporting Biotech Innovation
Raleigh-Durham-Chapel Hill Area, United States, United States1criver.com
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