PhoenixBio established its proprietary chimeric mouse model, the PXB-mouse®, with a highly humanized liver through years of research and development. With the addition of fresh, isolated human hepatocytes, PXB-cells®, the applications of our products and study services are as wide-ranging as our clients’ research goals.
The PXB-mouse animal background (cDNA-uPA/SCID) makes for a robust, consistent model that maintains up to 95% stable human hepatocyte engraftment. The reconstituted humanized liver features structural and biological characteristics commonly observed in normal human livers.
The model has proven to be a world-wide gold standard for Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) research, but usage is expanding in the fields of:
. Drug Metabolism and Pharmacokinetics,
· Human Specific Hepatotoxicity,
· Oligonucleotide and Gene-based Therapeutics,
· HBV & HBV/HDV,
· NASH/NAFLD,
· Other human liver-related research fields.
PXB-cells® are approximately 95% pure human hepatocytes freshly isolated from the PXB-mouse®. They feature long-term stability of up to 40 days, and allow for consistent supply from the same donor. One unique feature of PXB-cells® and PXB-mice is the ability to directly compare in vitro and in vitro data from the same human donor.
With over 300 scientific publications to its credit, the PXB-mouse is the world’s most widely used chimeric mouse model with a humanized liver. A high replacement index, lifespan of up to 2 years, and no secondary drug to maintain mouse liver injury means that your data can translate better to humans than ever before.
Please visit our website at https://www.phoenixbio.com/ to learn more about our model and inquire about our offered products and services.
Company Details
- Employees
- 24
- Founded
- -
- Address
- 3-4-1, Kagamiyama, Higashi-Hiroshima City,hiroshima 739-0046,japan
- Industry
- Biotechnology Research
- NAICS
-
Research and Development in Biotechnology (except Nanobiotechnology)
- Website
- phoenixbio.co.jp
- Keywords
- Biotechnology, Contract Research, Study Services, Project Management, Logistics, Drug Development, Drug metabolism, Safety, Toxicity, Pharmaceuticals, Efficacy testing, Humanized model, Hepatocytes.
- HQ
- Higashi-Hiroshima City, Hiroshima
Phoenixbio Questions
Phoenixbio's website is phoenixbio.co.jp
Phoenixbio's LinkedIn profile is https://www.linkedin.com/company/phoenixbio
Phoenixbio has
24 employees.
View email and phone details for 24
employees at Phoenixbio.
Phoenixbio's industry is
Biotechnology Research
Phoenixbio's top competitors are
Btig,
Kmt Hepatech, Inc. - Phoenixbio Group,
Fenfyre,
Research Diets, Inc.,
Recursion,
Onesoftware Powered By Flexschema,
Glyco Biologics Inc.,
Orbital Therapeutics,
Molscreen,
Yecuris Corporation.
Phoenixbio's categories are Biotechnology Research
Phoenixbio's founding year is 2002
