Verified email-pattern data for Senex Biotechnology. Inc. is currently limited. You can still use the company insights and contact sections below.
Senex is a clinical stage company focused on preventing transcriptional reprogramming, a process by which cancer cells modify gene expression to adapt to adversarial conditions; such adaptation leads to cancer drug resistance and metastasis. Senex’s lead program targets CDK8/19 Mediator Kinase, a protein complex that regulates transcription, but not cell cycle progression. Since CDK8/19 is not essential for adult organisms, its inhibition suppresses drug resistance and metastasis without unwanted side effects. Senex is developing highly selective small-molecule inhibitors of this protein for the treatment of presently incurable types of prostate cancer and breast cancer.
The Company’s lead clinical program, targeting castration resistant prostate cancer (CRPC), is currently supported by a $1.05 million Translational Science Award from the Department of Defense Prostate Cancer Program (DoD PCRP). “The preliminary data are robust and comprehensive in their support and validation of their goal to take SNX631-6 to clinical trials for the treatment of CRPC,” DoD PCRP reviewer.
SNX631-6, the Company’s clinical candidate, is an orally available, selective CDK8/19 inhibitor with nanomolar potency, outstanding selectivity, favorable pharmacokinetics and supratherapeutic toleration in repeat dose range finding studies in murine and primate models. “The preliminary data convincingly indicate the ability of SNX631-6 to inhibit development in CRPC of drug resistance, inhibit growth of bone-resident tumors, inhibit angiogenesis, and suppress expression of tumor-promoting genes in the cancer cells”, DoD PCRP reviewer.
Company Details
- Employees
- 7
- Founded
- -
- Address
- Columbia, Sc
- Phone
- 803-777-6161
- in****@****bio.com
- Industry
- Biotechnology Research
- Website
- senexbio.com
- Keywords
- Providence.
- HQ
- Columbia, SC
Senex Biotechnology. Inc. Questions
Senex Biotechnology. Inc.'s helpline number is 803-777-6161
Senex Biotechnology. Inc.'s website is senexbio.com
Senex Biotechnology. Inc.'s LinkedIn profile is https://www.linkedin.com/company/senex-biotechnology
Senex Biotechnology. Inc. has
7 employees.
View email and phone details for 7
employees at Senex Biotechnology. Inc..
Senex Biotechnology. Inc.'s industry is
Biotechnology Research
Senex Biotechnology. Inc.'s top competitors are
Biocentric Health Research,
Vista Clinical Research Group,
Aravis Biotech Llc,
Alexion Pharmaceuticals, Inc.,
Viridian Therapeutics, Inc.,
Invocares Foundation,
Elastrin Therapeutics,
South Carolina Clinical Research Llc.,
Perkin Industries,
J.w. Rew Company.
Senex Biotechnology. Inc.'s support email address is info@senexbio.com
Senex Biotechnology. Inc.'s categories are Biotechnology Research
Senex Biotechnology. Inc.'s founding year is 2002
Explore related pages
Related company profiles:
Top Senex Biotechnology. Inc. Employees
-
-
Igor B. Roninson
Professor, Endowed Chair At University…
Lexington, South Carolina, United States, United States4ordwayresearch.org, sc.edu, ordwayresearch.org, senexbio.com -
Zach Mack
Postdoctoral Research Fellow At Senex…
Columbia, South Carolina, United States, United States
Free Chrome Extension
Find emails, phones & company data instantly
Find verified emails from LinkedIn profiles
Get direct phone numbers & mobile contacts
Access company data & employee information
Works directly on LinkedIn - no copy/paste needed
Aero Online
Your AI prospecting assistant
Select data to include:
Total price:
$0.00
0 records × $0.02 per record
How It Works
Get a Free Account
Sign up for a free account. No credit card required. Up to 10 free credits.
Search the #1 Contact Database
Get contact details of over 750M+ profiles across 60M companies – all with industry-leading accuracy. Sales Navigator and Recruiter users, try out our Email Finder Extension.
Use our AI-Powered Email Finder
Find business and personal emails and mobile phone numbers with exclusive coverage across niche job titles, industries, and more for unparalleled targeting. Also available via our Contact Data API.