Aastha Jindal Email & Phone Number

Boston, Massachusetts, United States

Watertown, Massachusetts, Us

Watertown, Ma, Us

- Led the development, validation, and transfer of GLP NAb assays to CROs for AAV based gene therapies - Produced data package for PK/PD modeling that included cell binding, receptor occupancy & internalization kinetics- Provided support for pre-IND studies in both rare disease and autoimmune disease related programs- Trained Scientists on dPCR/ddPCR instruments, developed protocols for routine viral titer assessments - Investigated the presence of antigen specific T-cells subsets in PBMCs of ImmTOR treated clinical samples - Other responsibilities include MSD ELISA assays, cell culture, documentation and CRO communications

Waterloo, Wisconsin, Us

- Assay development and optimization (ELISA, PCR), Experienced in GLP/GMP environment.- Experienced in water activity measurements using Aqualab 3 and skala control.- Experienced in quality compliance, certificate of analysis and QC documentation.- Preparing large scale emulsions for animal immunizations for antibody generation.

Doylestown, Pennsylvania, Us

- Developed cell-based assays for evaluating mechanism of action of CDK inhibitor Milciclib.- Tested the efficacy of CDK and RTK inhibitor drugs in an orthotopic mouse model of HCC.- Performed in vitro toxicity studies of Milciclib & Sorafenib on hepatocytes & HCC cell lines.- Designed combination studies for CDK & RTK inhibitors in orthotopic HCC mouse model.- Developed cell-based assays to evaluate combination of CDK & EGFR inhibitors for NSCLC.- Designed cell-based assays for testing the efficacy of Foralumab, an anti-CD3 antibody. - Tested efficacy of dolcanatide in DSS-induced colitis & miRNA sequencing through CRO.- Managed CRO communications, analyzed data, drawn conclusions & project directions.

Madison, Wi, Us

- Investigated intracellular binding partners of TCP1 protein involved in type 2 diabetes.- Worked on standardizing immunoprecipitation protocol to purify TCP1 protein.

Worcester, Ma, Us

- Investigated the role of MCP1 in the pathogenesis of Alcoholic Liver Disease.

Vercelli, Vercelli, It

- Identified the role of oxidative stress in activating immune responses during NASH.- Discovered the role of inflammatory monocytes, dendritic cells & T-cells in NASH.- Investigated the role of natural killer T-cell in inflammation and steatohepatitis.- Investigated the role of fat-laden macrophages to modulate liver inflammation- Identified the property of macrophage secreted Annexin A1 to ameliorate liver inflammation.

Ghedi, Lombardia, It

- Developed low cost currency remittance program for low income immigrant farmers.- Enabled international rapport between banks & uneducated farmers.- Product development of prepaid card through conceptualization & market research.

Delhi, Delhi, In

- Organized training & orientation sessions for 5 team members to implement sales target.- Strategized sales improvement programs & marketing of scientific equipment.- Designed new sales strategy that increased the sales of bench-top centrifuges by 8%.

- Performed identification, characterization, and production of oil-degrading organisms.- Increased culture production to industrial scale for treating large volume oil sludge.

Bucharest, Ro

- Performed comparative studies of ammonium sulphate and caprylic acid purification methods for the isolation of anti-diphtheria serum (IgG).

Chicago, Us

- Performed production and testing of Japanese Encephalitis vaccine.

Doctor Of Philosophy (Phd), Molecular Medicine

Master Of Business Administration (M.B.A.), Management Of Global Business & Sustainability

Master'S Degree, Biotechnology

Engineer'S Degree, Biotechnology