Abe Garado Email & Phone Number

California, United States

Houston, Tx, Us

Houston, Texas, United States

BioProcess Development, MSATDeveloped Solugen’s enzyme fermentation and recovery manufacturing process with 58x increase in titer and 30x cost improvement over first-generation processDesigned BPD pilot lab (300 L scale), worked with senior leadership and engineering team to size, procure, install and commission pilot scale fermentation and DSP equipment as well as specify utility, power, and waste handling requirements and infrastructureLead team of 6 engineers, scientists, and technicians through pilot lab start-up, stabilization, as well as ongoing bioprocess discovery, development, optimization, scale-up, and technology transfer from bench to pilot and beyondWork closely with Sr. Director to develop and execute larger departmental strategy and goals: hiring, budgeting, internal talent and expertise growth and development, manage external CRO/CDMO relationships Unit operations developed: fermentation, centrifugation, chemical and mechanical lysis, normal flow filtration, tangential flow filtration (concentration and diafiltration)

Houston, Texas, United States

BioProcess DevelopmentRapidly developed and optimized microbial fermentation and recovery of industrial enzyme, demonstrating process robustness and scalability from flask to 3,000 L in 11 months (30,000x). Assembled BPD bench scale lab from off-the-shelf fermentation, recovery, and analytical equipment.Enzyme fermentation production and recovery increased from mg to kg scaleLead BPD’s communication and work with multiple CROs/CMOs and overseeing scale-down and scale-up processes and technology transfer Lead team of scientists and engineers responsible for continued development and optimization of Solugen bioprocess

Redwood City, California, United States

Fermentation, Pilot PlantResponsible for the management, training, development, and safety of a team of Research Associates (3 FTE) tasked with Redwood City Pilot Plant production and development fermentation and enzyme recovery operations. Provide direct operational and process oversight and troubleshooting for the plant. Work closely with Plant Director, Fermentation Development/Tech Transfer, and Business Operations groups to formulate weekly and monthly schedules balancing customer demand and development priorities as well as plant construction projects and capacity. Assign weekly and daily tasks as necessary to ensure production and development goals are met. Ensure adherence to SOPs, BPRs, safety and company policies. Investigate/document deviations and implement CAPAs as well as design and execute improvements through CCRs.

Emeryville, Ca

Process Development & Engineering, Pilot PlantManaged, trained, developed, and ensured the safety of a technical team of BioProcess Development Associates (5 FTE) responsible for all Emeryville pilot scale down-stream process activities for multiple target molecules including: scale-up, development, results validation, scale-down, and sample production utilizing multiple separation methods and unit operations.Executed yeast fermentations from vial thaw through production tank harvest (20 L – 1k L SS reactors, utilizing a multitude of feedstocks and growth strategies). Provided troubleshooting of fermentation and DSP processes, equipment, and utilities. Provide on-site and off-site technical support for processes transferred to CMOs abroad (100 m3 - 250 m3 scale, South America and Europe).Core contributor to the development and implementation of several DSP trains successfully recovering significantly different target molecules at pilot scale and subsequent transfer and scale-up to international pilot and manufacturing facilities.

Hayward, Ca

DNA Sequencing, Reagents & Flow CellsSupported the Development and Implementation of new Consumable Products and Consumables Manufacturing Processes.

Emeryville, Ca

Biopharmaceuticals Manufacturing, InspectionManaged all dayshift operations (24 FTE) in the Final Container Inspection Department.

Biopharmaceuticals Manufacturing, Pilot PlantFermentation and Primary Recovery of biopharmaceuticals.

Biopharmaceuticals Manufacturing, FinishingLed a team responsible for the labeling and packaging of biopharmaceuticals.