Adam Lyons Email & Phone Number

Boston, Ma, Us

Easton, Ma, Us

Cambridge, Massachusetts, United States

- Team specialist in normal flow filtration. Developed filtration steps and maintained filter inventories. Trained team members and other peers how to operate and scale harvest and final filtration.- Optimized harvest filtration to improve cell removal and filter loading while preventing introduction of impurities. Screened alternate filter types, designed filtration assemblies, and successfully scaled up from 30 mL to 40 L.- Screened formulations for final filtration. Assessed the existing filter train to reduce SVP concentration and increase product yield. Successfully scaled up from 2 L batch size to 40 L batch size.- Independently prepared and operated TFF to concentrate and buffer exchange product. Independently processed experimental and analytical data. Performed TMP excursions to identify the optimal TMP setting. - Prepared and operated AKTA FPLC in linear gradient, cycling, and routine production. Experience in AEX, CEX, and pseudo-affinity bind and elute strategies, as well as mixed-mode flowthrough applications across various matrices.- Diligently analyzed filter loading, analytics, and potency readouts. Documented findings in Benchling ELN. Calculated product recovery and impurity removal and made batch-to-batch comparisons, identifying trends and outliers to better understand filtration performance. Compiled all historical data into data reviews to present to the team.- Trained to operate assays shown above to reduce the sample burden on the analytical team. - Organized ELN templates to automate calculations and streamline data processing in JMP. Contributed to batch summary entries which calculated process yields and impurity reductions across all unit operations.

Andover, Massachusetts, United States

- Trended and analyzed GMP manufacturing and IEX data for multiple product lines to support department goals- Generated linear regression models using JMP to relate IEX process parameters and crude purity to elution profile and utilized this model to predict process output. Verified the model using IEX data from a pilot scale campaign- Gave multiple presentations to the PD department detailing project progress- Observed IEX chromatography, tangential flow filtration, and lyophilization unit operations at pilot scale- Authored a study report that characterized the IEX elution profile of a single product, identified a means of relating HPLC IPC data to fraction concentration, and recommended an improvement to IPC impurity region identification based on relative retention time

Amherst, Massachusetts, United States

- Led office hours to aid students with questions on homework and class material, and communicated closely with professor - Maintained integrity by grading homework and exams fairly, and organized solutions to grade efficiently

Wakefield, Rhode Island, United States

- Gained increased responsibility over multiple years resulting in appointment to lead counselor in summer 2021

North Easton, Massachusetts, United States

- Oversaw accurate monetary transactions in fast-paced environment while providing high-quality customer service

Wakefield, Rhode Island, United States

- Led 10-12 campers aged 12-15 years old each session, constantly monitoring well-being and communicating daily schedules - Assisted in training new counselors in the cabin and waterfront, including international members and provided staff support - Co-led waterfront activities daily, ranging from fishing to boat driving, working as a team with present staff

Bachelor'S Degree, Chemical Engineering

Concentration in Biochemical Engineering

Education record

Activities and Societies: Ice Hockey, National Honors Society